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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF605 All Species: 12.12
Human Site: S491 Identified Species: 66.67
UniProt: Q86T29 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86T29 NP_899061.1 641 74376 S491 K T F S E K S S L I H H Q R T
Chimpanzee Pan troglodytes A2T759 682 76399 N531 K T F G R S S N L I L H Q R V
Rhesus Macaque Macaca mulatta XP_001084023 639 74478 S489 K T F S E K S S L I H H Q R T
Dog Lupus familis XP_543345 649 75073 S492 K T F S E K S S L I H H Q R T
Cat Felis silvestris
Mouse Mus musculus Q80W31 679 77298 S529 K A F S Q I A S L T L H L R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.5 95.9 87 N.A. 47.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57 97.8 92.1 N.A. 62.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 100 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 20 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 60 100 0 0 0 % H
% Ile: 0 0 0 0 0 20 0 0 0 80 0 0 0 0 0 % I
% Lys: 100 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 100 0 40 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 20 0 0 0 0 0 0 0 80 0 0 % Q
% Arg: 0 0 0 0 20 0 0 0 0 0 0 0 0 100 0 % R
% Ser: 0 0 0 80 0 20 80 80 0 0 0 0 0 0 20 % S
% Thr: 0 80 0 0 0 0 0 0 0 20 0 0 0 0 60 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _