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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF180 All Species: 4.24
Human Site: T125 Identified Species: 18.67
UniProt: Q86T96 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86T96 NP_001107033.1 592 68254 T125 S R T D Y Q P T Q A G R L M R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086692 840 94883 A373 S R T D Y Q P A Q A G G L M R
Dog Lupus familis XP_544359 592 68268 T125 S W T D Y Q P T R A G R L M R
Cat Felis silvestris
Mouse Mus musculus Q3U827 592 67352 A126 S R T D H Q A A Q G G R L M R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506338 256 29076
Chicken Gallus gallus XP_429137 794 88211 A325 S R T D Y Q A A C S V K L A K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 68.4 87.5 N.A. 82 N.A. N.A. 33.7 38.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 69.1 93.7 N.A. 88.6 N.A. N.A. 37.8 50.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 86.6 86.6 N.A. 73.3 N.A. N.A. 0 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 93.3 N.A. 80 N.A. N.A. 0 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 34 50 0 50 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % C
% Asp: 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 17 67 17 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 17 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 84 0 0 50 0 0 0 0 0 0 % Q
% Arg: 0 67 0 0 0 0 0 0 17 0 0 50 0 0 67 % R
% Ser: 84 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % S
% Thr: 0 0 84 0 0 0 0 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % V
% Trp: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _