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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYPN
All Species:
12.12
Human Site:
S643
Identified Species:
33.33
UniProt:
Q86TC9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TC9
NP_115967.2
1320
145257
S643
A
T
K
T
P
E
P
S
S
P
V
K
E
P
P
Chimpanzee
Pan troglodytes
XP_001152308
1106
122026
R495
R
I
L
Q
K
K
P
R
S
T
A
E
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001082273
1107
122073
R496
R
I
L
Q
K
K
P
R
S
T
A
E
P
E
E
Dog
Lupus familis
XP_546131
1322
144963
S643
A
A
K
I
P
E
P
S
S
P
V
K
E
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5DTJ9
1315
144095
S640
E
A
R
I
P
E
P
S
S
P
I
K
E
P
P
Rat
Rattus norvegicus
P0C5E3
603
66686
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508648
1251
135560
K620
S
P
L
E
P
T
P
K
K
P
L
E
K
Q
Q
Chicken
Gallus gallus
XP_421565
1328
146338
T650
P
V
K
I
P
E
P
T
S
P
S
K
E
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700400
2113
232632
T1255
F
P
S
A
F
R
P
T
P
N
V
M
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
36.7
92.9
N.A.
87.5
27.4
N.A.
30.1
67.3
N.A.
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.7
51.9
95.3
N.A.
92.4
35.9
N.A.
46.8
79.1
N.A.
46.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
86.6
N.A.
66.6
0
N.A.
20
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
86.6
N.A.
80
0
N.A.
46.6
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
23
0
12
0
0
0
0
0
0
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
12
0
0
12
0
45
0
0
0
0
0
34
45
23
23
% E
% Phe:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
0
34
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
34
0
23
23
0
12
12
0
0
45
12
0
0
% K
% Leu:
0
0
34
0
0
0
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
12
23
0
0
56
0
89
0
12
56
0
0
23
45
45
% P
% Gln:
0
0
0
23
0
0
0
0
0
0
0
0
0
12
12
% Q
% Arg:
23
0
12
0
0
12
0
23
0
0
0
0
0
0
0
% R
% Ser:
12
0
12
0
0
0
0
34
67
0
12
0
0
12
0
% S
% Thr:
0
12
0
12
0
12
0
23
0
23
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _