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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM150A
All Species:
25.76
Human Site:
T259
Identified Species:
62.96
UniProt:
Q86TG1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TG1
NP_001026908.1
271
28835
T259
S
G
S
S
S
T
S
T
H
L
N
C
A
P
E
Chimpanzee
Pan troglodytes
XP_001167823
218
22988
H207
G
S
S
S
T
S
T
H
L
N
C
A
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001087786
271
28832
T259
S
G
S
S
S
T
S
T
H
L
N
C
A
P
E
Dog
Lupus familis
XP_540195
271
28947
T259
S
G
S
S
S
T
S
T
H
L
N
C
A
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN2
271
29047
T259
S
G
S
S
S
T
S
T
H
L
N
C
A
P
E
Rat
Rattus norvegicus
Q9QZE9
271
29031
T259
S
G
S
S
S
T
S
T
H
L
N
C
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514057
247
26271
T235
P
G
S
S
S
T
S
T
H
L
H
C
A
P
E
Chicken
Gallus gallus
XP_421633
260
28349
D249
P
K
S
H
K
G
E
D
S
L
P
G
T
E
G
Frog
Xenopus laevis
Q6GPL4
271
29386
T259
P
G
S
S
S
T
S
T
Q
L
H
C
N
A
E
Zebra Danio
Brachydanio rerio
Q32PK2
232
25997
N221
E
G
L
K
V
A
N
N
D
N
V
V
W
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
98.8
90.7
N.A.
91.5
92.2
N.A.
76.3
53.8
69.3
27.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.2
99.6
94.8
N.A.
95.5
97
N.A.
83.7
69.3
84.5
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
86.6
13.3
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
93.3
13.3
73.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
10
60
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
70
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
0
0
0
0
20
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
80
0
0
0
10
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
10
0
0
0
10
60
0
20
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
10
80
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
20
50
0
10
0
0
% N
% Pro:
30
0
0
0
0
0
0
0
0
0
10
0
10
60
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
10
90
80
70
10
70
0
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
10
70
10
70
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _