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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D1
All Species:
13.33
Human Site:
Y625
Identified Species:
48.89
UniProt:
Q86TI0
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TI0
NP_055988.2
1168
133084
Y625
S
Q
R
K
L
M
R
Y
H
S
V
S
T
E
T
Chimpanzee
Pan troglodytes
XP_001137680
1168
132983
Y625
S
Q
R
K
L
M
R
Y
H
S
V
S
T
E
T
Rhesus Macaque
Macaca mulatta
XP_001087581
1169
132693
Y625
S
Q
R
K
L
M
R
Y
H
S
V
S
T
E
T
Dog
Lupus familis
XP_863618
1170
132449
Y626
S
Q
R
K
F
M
R
Y
H
S
V
S
T
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60949
1255
142006
D712
L
K
F
L
A
P
V
D
E
N
N
T
C
D
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513119
1090
120577
L601
I
L
Q
Q
I
L
L
L
R
M
E
K
E
N
R
Chicken
Gallus gallus
Q5ZJ17
816
92547
I327
L
S
N
K
E
L
A
I
E
R
C
F
G
M
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.1
90.7
N.A.
83.9
N.A.
N.A.
55.4
22.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.8
94.6
N.A.
87.4
N.A.
N.A.
65.4
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
15
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
0
15
0
0
0
29
0
15
0
15
58
0
% E
% Phe:
0
0
15
0
15
0
0
0
0
0
0
15
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
15
0
0
15
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
72
0
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
29
15
0
15
43
29
15
15
0
0
0
0
0
0
15
% L
% Met:
0
0
0
0
0
58
0
0
0
15
0
0
0
15
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
15
15
0
0
15
0
% N
% Pro:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
58
15
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
58
0
0
0
58
0
15
15
0
0
0
0
15
% R
% Ser:
58
15
0
0
0
0
0
0
0
58
0
58
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
58
0
58
% T
% Val:
0
0
0
0
0
0
15
0
0
0
58
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _