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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4D All Species: 19.39
Human Site: S15 Identified Species: 30.48
UniProt: Q86TL0 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TL0 NP_116274.3 474 52922 S15 A A Q Y R S S S P E D A R R R
Chimpanzee Pan troglodytes XP_512373 411 46398
Rhesus Macaque Macaca mulatta XP_001101860 474 52893 S15 A A Q Y R S S S P E D A R R R
Dog Lupus familis XP_542069 473 52729 S15 A A Q Y R S G S P E D A R R P
Cat Felis silvestris
Mouse Mus musculus Q8BGV9 474 52892 S15 A A Q Y R S G S S E D A R R A
Rat Rattus norvegicus NP_001094483 473 52805 S15 A A Q Y R S G S P E D A R R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 S18 K I K T K F I S A W N N M K Y
Chicken Gallus gallus Q6PZ02 393 44512
Frog Xenopus laevis Q68FJ9 469 52793 K15 A T Q Y G S P K G S Q Q M E N
Zebra Danio Brachydanio rerio Q6DG88 394 44435
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 A92 N L K T E N A A T A T P Q R K
Honey Bee Apis mellifera XP_393739 477 54008 S16 R E R L G G F S N S T I G L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 G23 A A E P A G A G A I D A Q M D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 S15 F V P Q Q C S S S S K S D T H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 A32 L V N A M E A A R A G A A E V
Conservation
Percent
Protein Identity: 100 84.8 98.5 94.3 N.A. 86.2 86.7 N.A. 44 26.5 53.3 27 N.A. 30.3 35 N.A. 30.8
Protein Similarity: 100 85.6 98.9 96.1 N.A. 90.9 91.1 N.A. 59.4 39.6 68.9 41.9 N.A. 44.4 49.2 N.A. 41.9
P-Site Identity: 100 0 100 86.6 N.A. 80 86.6 N.A. 6.6 0 26.6 0 N.A. 6.6 6.6 N.A. 26.6
P-Site Similarity: 100 0 100 86.6 N.A. 80 86.6 N.A. 33.3 0 26.6 0 N.A. 46.6 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. 22.1
Protein Similarity: N.A. N.A. N.A. 42.4 N.A. 36.3
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 40 0 7 7 0 20 14 14 14 0 47 7 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 40 0 7 0 7 % D
% Glu: 0 7 7 0 7 7 0 0 0 34 0 0 0 14 0 % E
% Phe: 7 0 0 0 0 7 7 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 14 14 20 7 7 0 7 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 7 0 0 0 0 7 0 0 7 0 7 0 0 0 % I
% Lys: 7 0 14 0 7 0 0 7 0 0 7 0 0 7 7 % K
% Leu: 7 7 0 7 0 0 0 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 14 7 0 % M
% Asn: 7 0 7 0 0 7 0 0 7 0 7 7 0 0 7 % N
% Pro: 0 0 7 7 0 0 7 0 27 0 0 7 0 0 14 % P
% Gln: 0 0 40 7 7 0 0 0 0 0 7 7 14 0 0 % Q
% Arg: 7 0 7 0 34 0 0 0 7 0 0 0 34 40 14 % R
% Ser: 0 0 0 0 0 40 20 54 14 20 0 7 0 0 0 % S
% Thr: 0 7 0 14 0 0 0 0 7 0 14 0 0 7 0 % T
% Val: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _