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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
6.67
Human Site:
S180
Identified Species:
10.48
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S180
G
L
G
P
P
E
L
S
G
S
A
S
P
S
R
Chimpanzee
Pan troglodytes
XP_512373
411
46398
R147
A
P
E
L
E
Q
E
R
R
H
R
Q
I
V
S
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S180
G
L
G
P
P
E
L
S
G
S
A
S
P
S
R
Dog
Lupus familis
XP_542069
473
52729
A179
G
L
G
P
S
E
P
A
G
L
A
S
P
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
P180
G
L
A
S
S
E
M
P
G
P
A
S
P
S
R
Rat
Rattus norvegicus
NP_001094483
473
52805
P179
G
L
A
S
S
E
M
P
G
P
A
S
P
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
R172
W
V
G
E
R
D
P
R
P
P
S
A
S
R
N
Chicken
Gallus gallus
Q6PZ02
393
44512
A128
Y
Y
S
I
H
Q
I
A
Q
M
G
V
G
E
G
Frog
Xenopus laevis
Q68FJ9
469
52793
E167
Y
R
H
F
V
E
M
E
P
I
R
S
S
S
P
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Q130
Y
S
I
H
Q
I
A
Q
M
G
V
G
E
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
S348
V
K
W
F
G
D
S
S
S
K
S
S
P
F
S
Honey Bee
Apis mellifera
XP_393739
477
54008
T200
Q
P
D
Q
P
I
K
T
E
Q
Q
K
L
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
F431
A
H
S
L
I
L
H
F
L
G
R
E
W
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
D165
R
D
T
T
Y
T
S
D
V
N
W
G
C
M
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
A236
R
S
G
Q
S
L
L
A
N
A
I
L
I
A
R
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
0
100
66.6
N.A.
60
60
N.A.
6.6
0
20
0
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
6.6
100
80
N.A.
66.6
66.6
N.A.
33.3
20
26.6
6.6
N.A.
33.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
14
0
0
0
7
20
0
7
34
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
7
0
0
14
0
7
0
0
0
0
0
7
0
% D
% Glu:
0
0
7
7
7
40
7
7
7
0
0
7
7
7
7
% E
% Phe:
0
0
0
14
0
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
34
0
34
0
7
0
0
0
34
14
7
14
7
7
7
% G
% His:
0
7
7
7
7
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
7
7
14
7
0
0
7
7
0
14
0
14
% I
% Lys:
0
7
0
0
0
0
7
0
0
7
0
7
0
0
7
% K
% Leu:
0
34
0
14
0
14
20
0
7
7
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
20
0
7
7
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
7
0
0
0
14
7
% N
% Pro:
0
14
0
20
20
0
14
14
14
20
0
0
40
0
7
% P
% Gln:
7
0
0
14
7
14
0
7
7
7
7
7
0
0
0
% Q
% Arg:
14
7
0
0
7
0
0
14
7
0
20
0
0
7
40
% R
% Ser:
0
14
14
14
27
0
14
20
7
14
14
47
14
34
14
% S
% Thr:
0
0
7
7
0
7
0
7
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
7
0
0
0
7
0
7
7
0
7
0
% V
% Trp:
7
0
7
0
0
0
0
0
0
0
7
0
7
0
0
% W
% Tyr:
20
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _