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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
19.09
Human Site:
S238
Identified Species:
30
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S238
R
L
V
E
L
G
Q
S
S
G
K
K
A
G
D
Chimpanzee
Pan troglodytes
XP_512373
411
46398
G185
K
K
A
G
D
W
Y
G
P
S
L
V
A
H
I
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S238
R
L
V
E
L
G
Q
S
S
G
K
K
A
G
D
Dog
Lupus familis
XP_542069
473
52729
S237
R
L
V
E
L
G
Q
S
S
G
K
K
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
S238
R
L
V
E
L
G
R
S
S
G
K
K
A
G
D
Rat
Rattus norvegicus
NP_001094483
473
52805
S237
R
L
V
E
L
G
Q
S
S
G
K
K
A
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
K223
Q
L
T
E
Y
G
K
K
S
G
K
T
A
G
D
Chicken
Gallus gallus
Q6PZ02
393
44512
H166
T
W
S
S
L
A
V
H
I
A
M
D
N
T
V
Frog
Xenopus laevis
Q68FJ9
469
52793
I233
Q
L
V
T
L
G
S
I
F
G
K
K
A
G
D
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
V168
W
S
R
L
A
V
H
V
A
M
D
N
T
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Q392
H
A
L
E
H
A
A
Q
E
N
A
D
F
D
N
Honey Bee
Apis mellifera
XP_393739
477
54008
L238
T
L
V
S
L
G
A
L
W
G
K
R
A
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
K482
I
G
Q
N
N
G
K
K
V
G
D
W
Y
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
E205
L
P
E
Q
E
Y
L
E
T
L
E
P
F
G
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
Y280
S
L
H
N
F
V
K
Y
G
A
T
A
C
G
K
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
6.6
100
100
N.A.
93.3
100
N.A.
60
6.6
66.6
0
N.A.
6.6
60
N.A.
20
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
73.3
6.6
73.3
6.6
N.A.
20
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
7
14
14
0
7
14
7
7
60
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
14
14
0
7
60
% D
% Glu:
0
0
7
47
7
0
0
7
7
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
7
0
0
0
14
0
0
% F
% Gly:
0
7
0
7
0
60
0
7
7
60
0
0
0
74
0
% G
% His:
7
0
7
0
7
0
7
7
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% I
% Lys:
7
7
0
0
0
0
20
14
0
0
54
40
0
0
7
% K
% Leu:
7
60
7
7
54
0
7
7
0
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% M
% Asn:
0
0
0
14
7
0
0
0
0
7
0
7
7
0
7
% N
% Pro:
0
7
0
0
0
0
0
0
7
0
0
7
0
0
7
% P
% Gln:
14
0
7
7
0
0
27
7
0
0
0
0
0
0
0
% Q
% Arg:
34
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% R
% Ser:
7
7
7
14
0
0
7
34
40
7
0
0
0
0
0
% S
% Thr:
14
0
7
7
0
0
0
0
7
0
7
7
7
7
0
% T
% Val:
0
0
47
0
0
14
7
7
7
0
0
7
0
7
14
% V
% Trp:
7
7
0
0
0
7
0
0
7
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
7
7
7
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _