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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4D All Species: 13.03
Human Site: S367 Identified Species: 20.48
UniProt: Q86TL0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TL0 NP_116274.3 474 52922 S367 C Q P T V D V S Q A D F P L E
Chimpanzee Pan troglodytes XP_512373 411 46398 Q305 Q P T V D V S Q A D F P L E S
Rhesus Macaque Macaca mulatta XP_001101860 474 52893 S367 C Q P T V D V S Q A D F P L E
Dog Lupus familis XP_542069 473 52729 S366 C Q P T V D V S Q A D F P L E
Cat Felis silvestris
Mouse Mus musculus Q8BGV9 474 52892 S367 C Q P T V D V S Q P S F P L E
Rat Rattus norvegicus NP_001094483 473 52805 N366 C Q P T V D V N Q A N F P L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 D345 D D S L I Y M D P H Y C Q S F
Chicken Gallus gallus Q6PZ02 393 44512 E287 H T T Q P A V E P S D S G C L
Frog Xenopus laevis Q68FJ9 469 52793 L353 G Y Q D N Y L L Y L D P H Y C
Zebra Danio Brachydanio rerio Q6DG88 394 44435 V288 P H T T Q P A V D P S E D G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 N521 C Q E M V D V N Q E N F S L H
Honey Bee Apis mellifera XP_393739 477 54008 L369 C Q E T V D V L K D N F S L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 K611 C Q Q V V D M K T R D F P L W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 V330 P R Y I P S L V A T F T F P Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 P400 Q R L F Y L D P H H P R P A L
Conservation
Percent
Protein Identity: 100 84.8 98.5 94.3 N.A. 86.2 86.7 N.A. 44 26.5 53.3 27 N.A. 30.3 35 N.A. 30.8
Protein Similarity: 100 85.6 98.9 96.1 N.A. 90.9 91.1 N.A. 59.4 39.6 68.9 41.9 N.A. 44.4 49.2 N.A. 41.9
P-Site Identity: 100 0 100 100 N.A. 86.6 86.6 N.A. 0 13.3 6.6 6.6 N.A. 53.3 53.3 N.A. 53.3
P-Site Similarity: 100 0 100 100 N.A. 86.6 100 N.A. 13.3 20 13.3 6.6 N.A. 66.6 66.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. 22.1
Protein Similarity: N.A. N.A. N.A. 42.4 N.A. 36.3
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 7 0 14 27 0 0 0 7 0 % A
% Cys: 54 0 0 0 0 0 0 0 0 0 0 7 0 7 7 % C
% Asp: 7 7 0 7 7 54 7 7 7 14 40 0 7 0 0 % D
% Glu: 0 0 14 0 0 0 0 7 0 7 0 7 0 7 34 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 14 54 7 0 7 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % G
% His: 7 7 0 0 0 0 0 0 7 14 0 0 7 0 14 % H
% Ile: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % K
% Leu: 0 0 7 7 0 7 14 14 0 7 0 0 7 54 14 % L
% Met: 0 0 0 7 0 0 14 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 14 0 0 20 0 0 0 0 % N
% Pro: 14 7 34 0 14 7 0 7 14 14 7 14 47 7 0 % P
% Gln: 14 54 14 7 7 0 0 7 40 0 0 0 7 0 7 % Q
% Arg: 0 14 0 0 0 0 0 0 0 7 0 7 0 0 0 % R
% Ser: 0 0 7 0 0 7 7 27 0 7 14 7 14 7 7 % S
% Thr: 0 7 20 47 0 0 0 0 7 7 0 7 0 0 7 % T
% Val: 0 0 0 14 54 7 54 14 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 7 7 0 7 14 0 0 7 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _