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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
28.79
Human Site:
S375
Identified Species:
45.24
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S375
Q
A
D
F
P
L
E
S
F
H
C
T
S
P
R
Chimpanzee
Pan troglodytes
XP_512373
411
46398
F313
A
D
F
P
L
E
S
F
H
C
T
S
P
R
K
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S375
Q
A
D
F
P
L
E
S
F
H
C
T
S
P
R
Dog
Lupus familis
XP_542069
473
52729
S374
Q
A
D
F
P
L
E
S
F
H
C
T
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
S375
Q
P
S
F
P
L
E
S
F
H
C
T
S
P
R
Rat
Rattus norvegicus
NP_001094483
473
52805
S374
Q
A
N
F
P
L
E
S
F
H
C
T
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
V353
P
H
Y
C
Q
S
F
V
D
V
S
I
K
D
F
Chicken
Gallus gallus
Q6PZ02
393
44512
P295
P
S
D
S
G
C
L
P
D
E
S
F
H
C
Q
Frog
Xenopus laevis
Q68FJ9
469
52793
Q361
Y
L
D
P
H
Y
C
Q
P
Y
I
D
T
S
K
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
F296
D
P
S
E
D
G
H
F
P
D
D
S
Y
H
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
S529
Q
E
N
F
S
L
H
S
F
H
C
K
S
P
R
Honey Bee
Apis mellifera
XP_393739
477
54008
S377
K
D
N
F
S
L
T
S
F
H
C
T
S
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S619
T
R
D
F
P
L
W
S
F
H
C
M
S
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
S338
A
T
F
T
F
P
Q
S
V
G
I
L
G
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
P408
H
H
P
R
P
A
L
P
Y
R
E
D
P
R
G
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
0
100
100
N.A.
86.6
93.3
N.A.
0
6.6
6.6
0
N.A.
66.6
66.6
N.A.
73.3
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
100
N.A.
0
20
26.6
6.6
N.A.
73.3
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
27
0
0
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
7
7
0
0
7
54
0
0
7
7
% C
% Asp:
7
14
40
0
7
0
0
0
14
7
7
14
0
7
0
% D
% Glu:
0
7
0
7
0
7
34
0
0
7
7
0
0
0
0
% E
% Phe:
0
0
14
54
7
0
7
14
54
0
0
7
0
0
7
% F
% Gly:
0
0
0
0
7
7
0
0
0
7
0
0
7
7
7
% G
% His:
7
14
0
0
7
0
14
0
7
54
0
0
7
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
14
7
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
7
7
0
20
% K
% Leu:
0
7
0
0
7
54
14
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
14
14
7
14
47
7
0
14
14
0
0
0
14
54
0
% P
% Gln:
40
0
0
0
7
0
7
7
0
0
0
0
0
0
7
% Q
% Arg:
0
7
0
7
0
0
0
0
0
7
0
0
0
14
54
% R
% Ser:
0
7
14
7
14
7
7
60
0
0
14
14
54
7
0
% S
% Thr:
7
7
0
7
0
0
7
0
0
0
7
40
7
0
0
% T
% Val:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
7
0
0
7
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _