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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
30.3
Human Site:
S380
Identified Species:
47.62
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S380
L
E
S
F
H
C
T
S
P
R
K
M
A
F
A
Chimpanzee
Pan troglodytes
XP_512373
411
46398
P318
E
S
F
H
C
T
S
P
R
K
M
A
F
A
K
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S380
L
E
S
F
H
C
T
S
P
R
K
M
A
F
A
Dog
Lupus familis
XP_542069
473
52729
S379
L
E
S
F
H
C
T
S
P
R
K
M
A
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
S380
L
E
S
F
H
C
T
S
P
R
K
M
A
F
A
Rat
Rattus norvegicus
NP_001094483
473
52805
S379
L
E
S
F
H
C
T
S
P
R
K
M
A
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
K358
S
F
V
D
V
S
I
K
D
F
P
L
E
S
F
Chicken
Gallus gallus
Q6PZ02
393
44512
H300
C
L
P
D
E
S
F
H
C
Q
H
P
P
C
R
Frog
Xenopus laevis
Q68FJ9
469
52793
T366
Y
C
Q
P
Y
I
D
T
S
K
N
D
F
P
L
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Y301
G
H
F
P
D
D
S
Y
H
C
Q
H
P
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
S534
L
H
S
F
H
C
K
S
P
R
K
L
K
A
S
Honey Bee
Apis mellifera
XP_393739
477
54008
S382
L
T
S
F
H
C
T
S
P
R
K
M
L
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S624
L
W
S
F
H
C
M
S
P
R
K
M
S
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
G343
P
Q
S
V
G
I
L
G
G
K
P
G
A
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
P413
A
L
P
Y
R
E
D
P
R
G
Y
T
A
E
E
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
0
0
0
N.A.
60
73.3
N.A.
66.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
6.6
20
13.3
N.A.
73.3
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
7
47
14
34
% A
% Cys:
7
7
0
0
7
54
0
0
7
7
0
0
0
7
7
% C
% Asp:
0
0
0
14
7
7
14
0
7
0
0
7
0
0
0
% D
% Glu:
7
34
0
0
7
7
0
0
0
0
0
0
7
7
7
% E
% Phe:
0
7
14
54
0
0
7
0
0
7
0
0
14
34
7
% F
% Gly:
7
0
0
0
7
0
0
7
7
7
0
7
0
0
0
% G
% His:
0
14
0
7
54
0
0
7
7
0
7
7
0
0
0
% H
% Ile:
0
0
0
0
0
14
7
0
0
0
0
0
0
14
0
% I
% Lys:
0
0
0
0
0
0
7
7
0
20
54
0
7
0
7
% K
% Leu:
54
14
0
0
0
0
7
0
0
0
0
14
7
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
7
47
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
7
0
14
14
0
0
0
14
54
0
14
7
14
14
0
% P
% Gln:
0
7
7
0
0
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
14
54
0
0
0
0
7
% R
% Ser:
7
7
60
0
0
14
14
54
7
0
0
0
7
14
20
% S
% Thr:
0
7
0
0
0
7
40
7
0
0
0
7
0
0
7
% T
% Val:
0
0
7
7
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
7
0
0
7
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _