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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
8.18
Human Site:
S57
Identified Species:
12.86
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S57
G
S
P
G
A
G
P
S
E
P
D
E
V
D
K
Chimpanzee
Pan troglodytes
XP_512373
411
46398
S30
T
S
F
S
K
I
S
S
I
H
L
C
G
R
R
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S57
G
S
P
G
A
G
Q
S
E
P
D
E
V
D
K
Dog
Lupus familis
XP_542069
473
52729
G56
G
S
P
A
A
A
P
G
E
P
D
E
V
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
A57
G
S
S
G
T
D
P
A
E
P
D
E
V
D
K
Rat
Rattus norvegicus
NP_001094483
473
52805
A57
G
S
T
G
T
D
P
A
E
P
D
E
V
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
S52
G
K
C
Y
H
F
K
S
E
E
D
D
G
I
P
Chicken
Gallus gallus
Q6PZ02
393
44512
L11
A
T
L
T
Y
D
T
L
R
F
E
Y
E
D
F
Frog
Xenopus laevis
Q68FJ9
469
52793
A46
D
A
T
L
D
G
E
A
D
E
V
D
K
L
K
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
F13
L
T
Y
D
S
L
R
F
G
E
I
E
D
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
A138
E
E
P
G
D
L
S
A
N
R
T
P
T
K
G
Honey Bee
Apis mellifera
XP_393739
477
54008
V52
S
M
D
D
S
N
V
V
T
E
V
D
S
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
G312
N
T
A
S
D
E
A
G
D
E
D
Q
S
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
F47
F
T
L
W
S
N
V
F
T
S
S
S
S
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
T95
L
S
Q
L
T
A
D
T
P
P
L
D
K
S
Q
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
13.3
93.3
80
N.A.
73.3
73.3
N.A.
26.6
6.6
13.3
6.6
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
20
93.3
80
N.A.
80
80
N.A.
33.3
20
40
20
N.A.
20
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
20
14
7
27
0
0
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
7
14
20
20
7
0
14
0
47
27
7
40
0
% D
% Glu:
7
7
0
0
0
7
7
0
40
34
7
40
7
7
0
% E
% Phe:
7
0
7
0
0
7
0
14
0
7
0
0
0
7
7
% F
% Gly:
40
0
0
34
0
20
0
14
7
0
0
0
14
0
7
% G
% His:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
7
0
0
7
0
% I
% Lys:
0
7
0
0
7
0
7
0
0
0
0
0
14
14
47
% K
% Leu:
14
0
14
14
0
14
0
7
0
0
14
0
0
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
14
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
27
0
0
0
27
0
7
40
0
7
0
0
14
% P
% Gln:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
0
7
0
7
7
0
0
0
7
7
% R
% Ser:
7
47
7
14
20
0
14
27
0
7
7
7
20
7
7
% S
% Thr:
7
27
14
7
20
0
7
7
14
0
7
0
7
0
0
% T
% Val:
0
0
0
0
0
0
14
7
0
0
14
0
34
7
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _