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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4D All Species: 23.64
Human Site: S84 Identified Species: 37.14
UniProt: Q86TL0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TL0 NP_116274.3 474 52922 S84 K Y G W V V K S R T S F S K I
Chimpanzee Pan troglodytes XP_512373 411 46398 L57 Q R D F V S R L W L T Y R R D
Rhesus Macaque Macaca mulatta XP_001101860 474 52893 S84 K Y G W A V K S R T S F S K I
Dog Lupus familis XP_542069 473 52729 S83 K Y G W A V K S R T S F S K I
Cat Felis silvestris
Mouse Mus musculus Q8BGV9 474 52892 S84 K Y G W A V K S R T S F S K I
Rat Rattus norvegicus NP_001094483 473 52805 S84 K Y G W A V K S R T S F S K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 F79 I S G N V D E F R K D F V S R
Chicken Gallus gallus Q6PZ02 393 44512 K38 K Y S V F T E K E E I L L D V
Frog Xenopus laevis Q68FJ9 469 52793 T73 G W S V K M K T T F S R S A P
Zebra Danio Brachydanio rerio Q6DG88 394 44435 D40 F S A L T E K D D I L A D V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 M165 K Y G W S G K M R Q T S F S K
Honey Bee Apis mellifera XP_393739 477 54008 V79 Y G W T I K V V K P N F S K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 T339 K Y G W T V K T K T N F S I H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 G74 Q V C T T R N G W T A F V K R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 T122 V R T T A T A T C L S D T S M
Conservation
Percent
Protein Identity: 100 84.8 98.5 94.3 N.A. 86.2 86.7 N.A. 44 26.5 53.3 27 N.A. 30.3 35 N.A. 30.8
Protein Similarity: 100 85.6 98.9 96.1 N.A. 90.9 91.1 N.A. 59.4 39.6 68.9 41.9 N.A. 44.4 49.2 N.A. 41.9
P-Site Identity: 100 6.6 93.3 93.3 N.A. 93.3 93.3 N.A. 26.6 13.3 20 6.6 N.A. 40 20 N.A. 60
P-Site Similarity: 100 46.6 93.3 93.3 N.A. 93.3 93.3 N.A. 33.3 26.6 40 6.6 N.A. 46.6 40 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. 22.1
Protein Similarity: N.A. N.A. N.A. 42.4 N.A. 36.3
P-Site Identity: N.A. N.A. N.A. 20 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 34 0 7 0 0 0 7 7 0 7 0 % A
% Cys: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 7 7 0 7 7 7 7 7 % D
% Glu: 0 0 0 0 0 7 14 0 7 7 0 0 0 0 7 % E
% Phe: 7 0 0 7 7 0 0 7 0 7 0 60 7 0 0 % F
% Gly: 7 7 54 0 0 7 0 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 0 0 0 7 0 0 0 0 7 7 0 0 7 34 % I
% Lys: 54 0 0 0 7 7 60 7 14 7 0 0 0 47 7 % K
% Leu: 0 0 0 7 0 0 0 7 0 14 7 7 7 0 0 % L
% Met: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 7 0 0 7 0 0 0 14 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % P
% Gln: 14 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 14 0 0 0 7 7 0 47 0 0 7 7 7 14 % R
% Ser: 0 14 14 0 7 7 0 34 0 0 47 7 54 20 0 % S
% Thr: 0 0 7 20 20 14 0 20 7 47 14 0 7 0 7 % T
% Val: 7 7 0 14 20 40 7 7 0 0 0 0 14 7 7 % V
% Trp: 0 7 7 47 0 0 0 0 14 0 0 0 0 0 0 % W
% Tyr: 7 54 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _