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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
21.82
Human Site:
S93
Identified Species:
34.29
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
S93
T
S
F
S
K
I
S
S
I
H
L
C
G
R
R
Chimpanzee
Pan troglodytes
XP_512373
411
46398
P66
L
T
Y
R
R
D
F
P
P
L
P
G
G
C
L
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
S93
T
S
F
S
K
I
S
S
I
H
L
C
G
R
R
Dog
Lupus familis
XP_542069
473
52729
S92
T
S
F
S
K
I
S
S
V
H
L
C
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
T93
T
S
F
S
K
I
S
T
V
H
L
C
G
R
C
Rat
Rattus norvegicus
NP_001094483
473
52805
S93
T
S
F
S
K
I
S
S
V
H
L
C
G
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
W88
K
D
F
V
S
R
I
W
L
T
Y
R
E
E
F
Chicken
Gallus gallus
Q6PZ02
393
44512
S47
E
I
L
L
D
V
T
S
R
L
W
F
T
Y
R
Frog
Xenopus laevis
Q68FJ9
469
52793
Y82
F
S
R
S
A
P
V
Y
L
L
G
E
R
Y
F
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
R49
I
L
A
D
V
T
S
R
L
W
F
T
Y
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Q174
Q
T
S
F
S
K
E
Q
P
V
W
L
L
G
R
Honey Bee
Apis mellifera
XP_393739
477
54008
P88
P
N
F
S
K
E
S
P
V
C
L
L
G
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
P348
T
N
F
S
I
H
K
P
I
W
F
L
G
K
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
S83
T
A
F
V
K
R
V
S
M
A
S
G
A
I
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
A131
L
S
D
T
S
M
S
A
A
P
T
G
S
Q
L
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
6.6
100
93.3
N.A.
80
86.6
N.A.
6.6
13.3
13.3
13.3
N.A.
6.6
40
N.A.
33.3
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
13.3
26.6
20
26.6
N.A.
13.3
60
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
7
0
0
7
7
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
34
0
7
20
% C
% Asp:
0
7
7
7
7
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
7
7
0
0
0
0
7
7
7
0
% E
% Phe:
7
0
60
7
0
0
7
0
0
0
14
7
0
0
14
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
20
54
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
34
0
0
0
0
0
% H
% Ile:
7
7
0
0
7
34
7
0
20
0
0
0
0
7
7
% I
% Lys:
7
0
0
0
47
7
7
0
0
0
0
0
0
14
7
% K
% Leu:
14
7
7
7
0
0
0
0
20
20
40
20
7
0
14
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
7
0
20
14
7
7
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% Q
% Arg:
0
0
7
7
7
14
0
7
7
0
0
7
7
40
40
% R
% Ser:
0
47
7
54
20
0
54
40
0
0
7
0
7
0
0
% S
% Thr:
47
14
0
7
0
7
7
7
0
7
7
7
7
0
0
% T
% Val:
0
0
0
14
7
7
14
0
27
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
14
14
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
7
0
0
7
0
7
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _