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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
20.3
Human Site:
T451
Identified Species:
31.9
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
T451
C
S
Q
L
A
Q
P
T
L
R
L
P
R
T
G
Chimpanzee
Pan troglodytes
XP_512373
411
46398
L389
S
Q
L
A
Q
P
T
L
R
L
P
R
T
G
R
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
T451
C
S
Q
L
S
Q
P
T
L
R
L
P
R
T
G
Dog
Lupus familis
XP_542069
473
52729
T450
C
S
Q
L
S
Q
P
T
L
R
L
P
R
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
T451
C
T
Q
L
S
Q
P
T
L
R
L
P
C
T
G
Rat
Rattus norvegicus
NP_001094483
473
52805
T450
C
T
Q
L
S
Q
P
T
L
R
L
P
C
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
A429
H
S
R
D
Y
D
F
A
S
G
P
T
R
E
E
Chicken
Gallus gallus
Q6PZ02
393
44512
S371
V
L
N
L
T
P
D
S
S
D
A
D
R
L
E
Frog
Xenopus laevis
Q68FJ9
469
52793
E437
I
S
E
G
Q
A
Q
E
Y
A
E
G
P
Q
S
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
F372
V
L
N
L
T
P
D
F
S
D
S
D
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Y605
T
E
Q
T
E
M
N
Y
P
L
F
S
F
S
R
Honey Bee
Apis mellifera
XP_393739
477
54008
S453
I
A
E
N
I
I
P
S
T
T
S
F
T
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
R695
T
N
T
N
R
P
E
R
Y
L
R
V
R
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
D414
F
Y
C
R
D
K
D
D
F
D
D
F
C
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
R484
A
R
G
Q
G
G
G
R
A
E
A
I
D
E
V
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
0
93.3
93.3
N.A.
80
80
N.A.
13.3
13.3
6.6
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
0
100
100
N.A.
93.3
93.3
N.A.
20
20
13.3
13.3
N.A.
13.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
7
7
0
7
7
7
14
0
0
0
0
% A
% Cys:
34
0
7
0
0
0
0
0
0
0
0
0
20
0
0
% C
% Asp:
0
0
0
7
7
7
20
7
0
20
7
14
7
0
0
% D
% Glu:
0
7
14
0
7
0
7
7
0
7
7
0
0
14
20
% E
% Phe:
7
0
0
0
0
0
7
7
7
0
7
14
7
0
0
% F
% Gly:
0
0
7
7
7
7
7
0
0
7
0
7
0
14
34
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
14
0
0
0
7
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
14
7
47
0
0
0
7
34
20
34
0
0
20
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
14
14
0
0
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
27
40
0
7
0
14
34
7
0
0
% P
% Gln:
0
7
40
7
14
34
7
0
0
0
0
0
0
7
0
% Q
% Arg:
0
7
7
7
7
0
0
14
7
34
7
7
47
0
20
% R
% Ser:
7
34
0
0
27
0
0
14
20
0
14
7
0
7
7
% S
% Thr:
14
14
7
7
14
0
7
34
7
7
0
7
14
34
0
% T
% Val:
14
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
7
14
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _