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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
21.82
Human Site:
Y101
Identified Species:
34.29
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
Y101
I
H
L
C
G
R
R
Y
R
F
E
G
E
G
D
Chimpanzee
Pan troglodytes
XP_512373
411
46398
T74
P
L
P
G
G
C
L
T
S
D
C
G
W
G
C
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
Y101
I
H
L
C
G
R
R
Y
R
F
E
G
E
G
D
Dog
Lupus familis
XP_542069
473
52729
Y100
V
H
L
C
G
R
R
Y
R
F
E
G
E
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
Y101
V
H
L
C
G
R
C
Y
H
F
E
G
E
G
D
Rat
Rattus norvegicus
NP_001094483
473
52805
Y101
V
H
L
C
G
R
C
Y
H
F
E
G
E
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
P96
L
T
Y
R
E
E
F
P
P
M
G
A
S
G
L
Chicken
Gallus gallus
Q6PZ02
393
44512
K55
R
L
W
F
T
Y
R
K
N
F
P
A
I
G
G
Frog
Xenopus laevis
Q68FJ9
469
52793
F90
L
L
G
E
R
Y
F
F
R
L
D
D
E
I
E
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
N57
L
W
F
T
Y
R
K
N
F
Q
P
I
G
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
C182
P
V
W
L
L
G
R
C
Y
H
R
R
F
T
P
Honey Bee
Apis mellifera
XP_393739
477
54008
Y96
V
C
L
L
G
K
I
Y
R
K
K
P
E
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
Y356
I
W
F
L
G
K
C
Y
H
Q
R
P
E
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
R91
M
A
S
G
A
I
R
R
F
Q
E
R
V
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
G139
A
P
T
G
S
Q
L
G
S
F
D
T
V
P
D
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
20
100
93.3
N.A.
80
80
N.A.
6.6
20
13.3
13.3
N.A.
6.6
33.3
N.A.
26.6
P-Site Similarity:
100
20
100
100
N.A.
86.6
86.6
N.A.
13.3
20
40
26.6
N.A.
6.6
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
0
0
0
14
0
0
0
% A
% Cys:
0
7
0
34
0
7
20
7
0
0
7
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
14
7
0
7
40
% D
% Glu:
0
0
0
7
7
7
0
0
0
0
40
0
54
7
7
% E
% Phe:
0
0
14
7
0
0
14
7
14
47
0
0
7
0
7
% F
% Gly:
0
0
7
20
54
7
0
7
0
0
7
40
7
60
14
% G
% His:
0
34
0
0
0
0
0
0
20
7
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
7
7
0
0
0
0
7
7
7
0
% I
% Lys:
0
0
0
0
0
14
7
7
0
7
7
0
0
0
0
% K
% Leu:
20
20
40
20
7
0
14
0
0
7
0
0
0
7
7
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
14
7
7
0
0
0
0
7
7
0
14
14
0
7
14
% P
% Gln:
0
0
0
0
0
7
0
0
0
20
0
0
0
0
0
% Q
% Arg:
7
0
0
7
7
40
40
7
34
0
14
14
0
0
0
% R
% Ser:
0
0
7
0
7
0
0
0
14
0
0
0
7
0
0
% S
% Thr:
0
7
7
7
7
0
0
7
0
0
0
7
0
7
7
% T
% Val:
27
7
0
0
0
0
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
14
14
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
7
14
0
47
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _