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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
32.73
Human Site:
Y247
Identified Species:
51.43
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
Y247
G
K
K
A
G
D
W
Y
G
P
S
L
V
A
H
Chimpanzee
Pan troglodytes
XP_512373
411
46398
R194
S
L
V
A
H
I
L
R
K
A
V
E
S
C
S
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
Y247
G
K
K
A
G
D
W
Y
G
P
S
L
V
A
H
Dog
Lupus familis
XP_542069
473
52729
Y246
G
K
K
A
G
D
W
Y
G
P
S
L
V
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
Y247
G
K
K
A
G
D
W
Y
G
P
S
V
V
A
H
Rat
Rattus norvegicus
NP_001094483
473
52805
Y246
G
K
K
A
G
D
W
Y
G
P
S
V
V
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
Y232
G
K
T
A
G
D
W
Y
G
P
A
V
V
A
H
Chicken
Gallus gallus
Q6PZ02
393
44512
M175
A
M
D
N
T
V
V
M
E
E
I
R
R
L
C
Frog
Xenopus laevis
Q68FJ9
469
52793
Y242
G
K
K
A
G
D
W
Y
G
P
S
I
V
A
H
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
E177
M
D
N
T
V
V
I
E
E
I
K
R
L
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
S401
N
A
D
F
D
N
I
S
V
Y
V
A
K
D
C
Honey Bee
Apis mellifera
XP_393739
477
54008
Y247
G
K
R
A
G
D
W
Y
G
P
S
S
V
A
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S491
G
D
W
Y
G
P
S
S
V
A
H
I
L
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
E214
L
E
P
F
G
D
S
E
P
S
A
F
S
I
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
P289
A
T
A
C
G
K
Y
P
G
E
W
F
G
P
S
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
80
0
93.3
0
N.A.
0
86.6
N.A.
13.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
0
100
6.6
N.A.
6.6
93.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
60
0
0
0
0
0
14
14
7
0
54
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
14
14
% C
% Asp:
0
14
14
0
7
60
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
7
0
0
0
0
0
14
14
14
0
7
0
0
7
% E
% Phe:
0
0
0
14
0
0
0
0
0
0
0
14
0
0
0
% F
% Gly:
60
0
0
0
74
0
0
0
60
0
0
0
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
60
% H
% Ile:
0
0
0
0
0
7
14
0
0
7
7
14
0
7
0
% I
% Lys:
0
54
40
0
0
7
0
0
7
0
7
0
7
7
0
% K
% Leu:
7
7
0
0
0
0
7
0
0
0
0
20
14
7
0
% L
% Met:
7
7
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
7
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
7
0
7
7
54
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
0
14
7
0
0
% R
% Ser:
7
0
0
0
0
0
14
14
0
7
47
7
14
0
14
% S
% Thr:
0
7
7
7
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
7
14
7
0
14
0
14
20
54
0
0
% V
% Trp:
0
0
7
0
0
0
54
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
54
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _