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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
25.76
Human Site:
Y317
Identified Species:
40.48
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
Y317
G
E
T
L
N
P
V
Y
V
P
C
V
K
E
L
Chimpanzee
Pan troglodytes
XP_512373
411
46398
C264
C
V
K
E
L
L
R
C
E
L
C
L
G
I
M
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
Y317
G
E
T
L
N
P
V
Y
V
P
C
V
K
E
L
Dog
Lupus familis
XP_542069
473
52729
Y316
G
E
T
L
N
P
V
Y
V
P
C
V
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
Y317
G
E
T
L
N
P
V
Y
V
P
C
V
K
E
L
Rat
Rattus norvegicus
NP_001094483
473
52805
Y316
G
E
T
L
N
P
V
Y
V
P
C
V
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
T302
V
R
L
G
G
E
R
T
N
I
D
Y
L
E
F
Chicken
Gallus gallus
Q6PZ02
393
44512
H245
A
Y
I
E
T
L
K
H
C
F
M
M
P
Q
S
Frog
Xenopus laevis
Q68FJ9
469
52793
T312
P
V
R
L
G
G
E
T
F
N
P
V
Y
K
H
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Q247
A
Y
I
E
P
L
K
Q
C
F
M
M
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Y471
S
D
K
L
N
P
V
Y
A
H
C
L
K
L
L
Honey Bee
Apis mellifera
XP_393739
477
54008
P317
L
G
A
D
K
L
N
P
V
Y
T
S
C
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
Y561
G
D
E
V
N
P
V
Y
I
R
P
I
Q
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
P284
D
G
E
R
G
G
A
P
I
L
C
I
E
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
V359
G
I
D
K
I
N
Q
V
Y
E
E
A
L
I
S
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
0
13.3
0
N.A.
53.3
6.6
N.A.
40
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
6.6
20
20
13.3
N.A.
66.6
6.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
0
0
7
0
7
0
0
7
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
7
14
0
54
0
7
0
0
% C
% Asp:
7
14
7
7
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
0
34
14
20
0
7
7
0
7
7
7
0
7
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
14
0
0
0
0
7
% F
% Gly:
47
14
0
7
20
14
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% H
% Ile:
0
7
14
0
7
0
0
0
14
7
0
14
0
14
0
% I
% Lys:
0
0
14
7
7
0
14
0
0
0
0
0
40
7
0
% K
% Leu:
7
0
7
47
7
27
0
0
0
14
0
14
14
14
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
14
0
0
7
% M
% Asn:
0
0
0
0
47
7
7
0
7
7
0
0
0
0
0
% N
% Pro:
7
0
0
0
7
47
0
14
0
34
14
0
14
0
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
0
0
7
14
0
% Q
% Arg:
0
7
7
7
0
0
14
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
0
7
0
7
20
% S
% Thr:
0
0
34
0
7
0
0
14
0
0
7
0
0
0
7
% T
% Val:
7
14
0
7
0
0
47
7
40
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
0
47
7
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _