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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
18.79
Human Site:
Y354
Identified Species:
29.52
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
Y354
Y
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
Chimpanzee
Pan troglodytes
XP_512373
411
46398
L292
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
P
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
Y354
Y
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
Dog
Lupus familis
XP_542069
473
52729
Y353
Y
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
Y354
Y
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
Rat
Rattus norvegicus
NP_001094483
473
52805
Y353
Y
Q
D
D
F
L
L
Y
L
D
P
H
Y
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
Y332
G
K
P
K
Q
S
Y
Y
F
A
G
F
Q
D
D
Chicken
Gallus gallus
Q6PZ02
393
44512
L274
I
G
Y
V
G
E
E
L
I
Y
L
D
P
H
T
Frog
Xenopus laevis
Q68FJ9
469
52793
H340
I
I
G
G
K
P
K
H
S
L
Y
F
I
G
Y
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
E275
F
I
G
F
V
G
D
E
L
I
Y
L
D
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
H508
F
Q
E
D
R
L
I
H
L
D
P
H
Y
C
Q
Honey Bee
Apis mellifera
XP_393739
477
54008
N356
F
Q
E
D
K
L
I
N
L
D
P
H
Y
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
H598
F
Q
E
E
K
L
I
H
L
D
P
H
Y
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
G317
L
L
V
P
L
V
L
G
L
D
S
V
N
P
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
F387
R
P
S
S
S
H
Y
F
V
G
V
Q
G
Q
R
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
0
0
6.6
N.A.
66.6
66.6
N.A.
60
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
13.3
6.6
6.6
13.3
N.A.
93.3
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
54
0
% C
% Asp:
0
7
40
47
0
0
7
0
7
60
0
7
7
7
7
% D
% Glu:
0
0
20
7
0
7
7
7
0
0
0
0
0
0
0
% E
% Phe:
27
0
0
14
34
0
0
7
7
0
0
14
0
0
0
% F
% Gly:
7
7
14
7
7
7
0
7
0
7
7
0
7
7
0
% G
% His:
0
0
0
0
0
7
0
20
0
0
7
54
0
7
7
% H
% Ile:
14
14
0
0
0
0
20
0
7
7
0
0
7
0
0
% I
% Lys:
0
7
0
7
20
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
0
0
14
60
40
14
67
7
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% N
% Pro:
0
7
7
7
0
7
0
0
0
7
54
0
7
14
7
% P
% Gln:
7
54
0
0
7
0
0
0
0
0
0
7
7
14
54
% Q
% Arg:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
14
% R
% Ser:
0
0
7
7
7
7
0
0
7
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
7
7
7
7
0
0
7
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
7
0
0
0
20
40
0
7
14
7
54
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _