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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM110
All Species:
28.18
Human Site:
S249
Identified Species:
62
UniProt:
Q86TL2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL2
NP_940965.1
294
33187
S249
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Chimpanzee
Pan troglodytes
XP_001152909
563
61430
S440
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001085822
372
41630
S249
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Dog
Lupus familis
XP_850114
291
33356
S246
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UF25
288
32481
S249
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Rat
Rattus norvegicus
Q7TSW6
288
32451
S249
V
R
Y
R
R
A
A
S
H
E
E
S
E
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505640
151
17342
L115
E
E
S
E
S
E
I
L
I
S
A
D
D
E
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088239
206
22963
V169
M
F
E
K
T
A
I
V
L
V
L
L
I
P
H
Zebra Danio
Brachydanio rerio
NP_956761
298
33677
S253
V
R
Y
R
R
A
L
S
H
D
D
S
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204058
274
31310
S237
Q
R
V
H
Y
Y
R
S
V
P
G
K
S
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P46621
176
19407
N140
V
E
Q
G
L
I
N
N
V
Q
Q
I
G
I
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
78.7
82.9
N.A.
95.5
95.9
N.A.
42.1
N.A.
52
73.8
N.A.
N.A.
N.A.
N.A.
42.1
Protein Similarity:
100
52
78.7
85
N.A.
95.5
95.9
N.A.
48.2
N.A.
59.1
86.2
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
20
93.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
21
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
73
55
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
10
10
0
10
% D
% Glu:
10
19
10
10
0
10
0
0
0
55
55
0
64
10
64
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
64
0
0
0
0
0
19
% H
% Ile:
0
0
0
0
0
10
19
0
10
0
0
10
10
10
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
10
10
0
10
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
73
0
64
64
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
73
0
10
0
64
10
73
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
73
0
10
0
0
0
0
10
19
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
64
0
10
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _