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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM110
All Species:
17.58
Human Site:
T278
Identified Species:
38.67
UniProt:
Q86TL2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL2
NP_940965.1
294
33187
T278
E
E
D
L
R
R
L
T
P
L
K
P
V
K
K
Chimpanzee
Pan troglodytes
XP_001152909
563
61430
T469
E
E
D
L
R
R
L
T
P
L
K
P
V
K
K
Rhesus Macaque
Macaca mulatta
XP_001085822
372
41630
T278
E
E
D
L
R
R
L
T
P
L
K
P
V
K
K
Dog
Lupus familis
XP_850114
291
33356
T275
E
E
D
L
R
R
L
T
P
L
K
P
A
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UF25
288
32481
V278
E
E
D
L
R
R
P
V
K
K
K
H
R
F
G
Rat
Rattus norvegicus
Q7TSW6
288
32451
V278
E
E
D
L
R
R
P
V
K
K
K
H
R
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505640
151
17342
K144
L
K
P
V
K
K
K
K
H
R
F
G
L
P
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088239
206
22963
L198
L
E
L
A
T
V
M
L
I
V
P
F
L
L
M
Zebra Danio
Brachydanio rerio
NP_956761
298
33677
T282
D
D
D
V
R
R
I
T
G
L
K
P
V
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204058
274
31310
L266
T
K
A
S
N
G
S
L
L
V
R
E
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P46621
176
19407
G169
I
L
L
V
S
L
I
G
A
I
T
M
A
R
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
78.7
82.9
N.A.
95.5
95.9
N.A.
42.1
N.A.
52
73.8
N.A.
N.A.
N.A.
N.A.
42.1
Protein Similarity:
100
52
78.7
85
N.A.
95.5
95.9
N.A.
48.2
N.A.
59.1
86.2
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
93.3
N.A.
46.6
46.6
N.A.
0
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
46.6
N.A.
33.3
N.A.
26.6
93.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
21
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
10
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
64
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
55
64
0
0
0
0
0
0
0
0
0
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
19
0
% F
% Gly:
0
0
0
0
0
10
0
10
10
0
0
10
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
19
0
0
0
% H
% Ile:
10
0
0
0
0
0
19
0
10
10
0
0
0
0
0
% I
% Lys:
0
19
0
0
10
10
10
10
19
19
64
0
0
46
46
% K
% Leu:
19
10
19
55
0
10
37
19
10
46
0
0
19
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
19
0
37
0
10
46
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
64
64
0
0
0
10
10
0
19
10
0
% R
% Ser:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
46
0
0
10
0
0
0
0
% T
% Val:
0
0
0
28
0
10
0
19
0
19
0
0
37
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _