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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX53
All Species:
7.88
Human Site:
S317
Identified Species:
19.26
UniProt:
Q86TM3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TM3
NP_874358.2
631
71154
S317
L
H
V
E
A
E
C
S
K
Y
S
Y
K
G
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087519
592
67036
G292
K
S
I
C
I
C
G
G
R
N
R
I
G
Q
I
Dog
Lupus familis
XP_853740
646
73189
S335
L
Q
V
E
A
E
C
S
K
Y
S
Y
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001060057
620
69575
S309
L
Q
V
E
A
E
C
S
K
Y
S
Y
G
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426195
445
49951
A149
G
I
D
L
I
G
I
A
Q
T
G
T
G
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19109
719
78529
E376
Q
I
Q
Q
V
A
T
E
F
G
S
S
S
Y
V
Honey Bee
Apis mellifera
XP_394925
593
68127
G291
K
A
V
C
L
Y
G
G
G
S
R
K
K
Q
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4R3
591
64603
L285
K
G
P
Q
I
R
D
L
R
R
G
V
E
I
V
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
M250
T
P
G
R
L
I
D
M
L
E
I
G
K
T
N
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
L266
C
I
A
T
P
G
R
L
I
D
M
L
E
S
G
Conservation
Percent
Protein Identity:
100
N.A.
84.4
65.3
N.A.
N.A.
60.2
N.A.
N.A.
46.9
N.A.
N.A.
N.A.
26.5
40.8
N.A.
N.A.
Protein Similarity:
100
N.A.
88.2
78.7
N.A.
N.A.
75.5
N.A.
N.A.
57.6
N.A.
N.A.
N.A.
45.9
59.1
N.A.
N.A.
P-Site Identity:
100
N.A.
0
93.3
N.A.
N.A.
80
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
93.3
N.A.
N.A.
80
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
35.3
33.1
Protein Similarity:
N.A.
N.A.
N.A.
53.8
54.2
51.5
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
30
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
20
0
10
30
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
20
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
30
0
30
0
10
0
10
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
0
20
20
20
10
10
20
10
30
20
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
30
10
0
30
10
10
0
10
0
10
10
0
10
10
% I
% Lys:
30
0
0
0
0
0
0
0
30
0
0
10
40
10
0
% K
% Leu:
30
0
0
10
20
0
0
20
10
0
0
10
0
0
30
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
20
10
20
0
0
0
0
10
0
0
0
0
20
0
% Q
% Arg:
0
0
0
10
0
10
10
0
20
10
20
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
30
0
10
40
10
10
10
0
% S
% Thr:
10
0
0
10
0
0
10
0
0
10
0
10
0
10
10
% T
% Val:
0
0
40
0
10
0
0
0
0
0
0
10
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
30
0
30
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _