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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX53
All Species:
9.39
Human Site:
T403
Identified Species:
22.96
UniProt:
Q86TM3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TM3
NP_874358.2
631
71154
T403
D
V
R
P
D
R
Q
T
V
M
T
S
A
T
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087519
592
67036
T363
D
V
H
P
D
R
Q
T
V
M
I
S
A
T
W
Dog
Lupus familis
XP_853740
646
73189
L412
E
P
Q
I
M
K
I
L
L
D
V
R
P
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001060057
620
69575
L386
E
P
Q
I
M
K
I
L
L
D
V
R
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426195
445
49951
K219
I
Y
G
G
G
D
R
K
A
Q
I
N
V
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19109
719
78529
S466
D
R
Q
T
L
M
W
S
A
T
W
P
K
E
V
Honey Bee
Apis mellifera
XP_394925
593
68127
T362
D
I
R
P
D
R
Q
T
V
M
T
S
A
T
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4R3
591
64603
V357
S
A
T
W
P
R
E
V
E
T
L
A
R
Q
F
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
Q320
L
N
D
P
I
Q
V
Q
V
G
S
L
E
L
S
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
I336
A
D
F
L
T
D
F
I
Q
V
N
I
G
S
M
Conservation
Percent
Protein Identity:
100
N.A.
84.4
65.3
N.A.
N.A.
60.2
N.A.
N.A.
46.9
N.A.
N.A.
N.A.
26.5
40.8
N.A.
N.A.
Protein Similarity:
100
N.A.
88.2
78.7
N.A.
N.A.
75.5
N.A.
N.A.
57.6
N.A.
N.A.
N.A.
45.9
59.1
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
0
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
93.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
26.6
N.A.
N.A.
26.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
20
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
35.3
33.1
Protein Similarity:
N.A.
N.A.
N.A.
53.8
54.2
51.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
20
0
0
10
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
10
10
0
30
20
0
0
0
20
0
0
0
20
0
% D
% Glu:
20
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
10
10
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
20
10
0
20
10
0
0
20
10
0
0
0
% I
% Lys:
0
0
0
0
0
20
0
10
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
10
10
0
0
20
20
0
10
10
0
10
0
% L
% Met:
0
0
0
0
20
10
0
0
0
30
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
20
0
40
10
0
0
0
0
0
0
10
20
0
0
% P
% Gln:
0
0
30
0
0
10
30
10
10
10
0
0
0
10
0
% Q
% Arg:
0
10
20
0
0
40
10
0
0
0
0
20
10
0
20
% R
% Ser:
10
0
0
0
0
0
0
10
0
0
10
30
0
10
10
% S
% Thr:
0
0
10
10
10
0
0
30
0
20
20
0
0
30
10
% T
% Val:
0
20
0
0
0
0
10
10
40
10
20
0
10
10
10
% V
% Trp:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
30
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _