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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX53
All Species:
11.52
Human Site:
T457
Identified Species:
28.15
UniProt:
Q86TM3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TM3
NP_874358.2
631
71154
T457
E
K
E
K
R
A
L
T
Q
E
F
V
E
N
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087519
592
67036
T417
E
E
E
K
R
A
L
T
Q
E
F
I
E
N
M
Dog
Lupus familis
XP_853740
646
73189
T466
V
K
Q
N
I
I
V
T
T
E
E
E
K
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001060057
620
69575
T440
V
K
Q
N
I
I
I
T
T
E
E
E
K
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426195
445
49951
I273
D
M
G
F
E
P
Q
I
M
K
I
L
I
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19109
719
78529
L520
E
E
K
L
K
T
L
L
S
D
I
Y
D
T
S
Honey Bee
Apis mellifera
XP_394925
593
68127
M416
E
E
E
K
T
D
M
M
Y
E
F
F
R
K
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4R3
591
64603
S411
L
K
Q
L
M
D
G
S
K
I
L
I
F
V
E
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
D374
A
S
T
K
R
M
C
D
D
I
T
K
Y
L
R
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
T390
K
I
L
I
F
T
G
T
K
R
V
A
D
D
I
Conservation
Percent
Protein Identity:
100
N.A.
84.4
65.3
N.A.
N.A.
60.2
N.A.
N.A.
46.9
N.A.
N.A.
N.A.
26.5
40.8
N.A.
N.A.
Protein Similarity:
100
N.A.
88.2
78.7
N.A.
N.A.
75.5
N.A.
N.A.
57.6
N.A.
N.A.
N.A.
45.9
59.1
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
20
N.A.
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
N.A.
13.3
40
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
40
N.A.
N.A.
40
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
46.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
35.3
33.1
Protein Similarity:
N.A.
N.A.
N.A.
53.8
54.2
51.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
20
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
20
0
10
10
10
0
0
20
20
0
% D
% Glu:
40
30
30
0
10
0
0
0
0
50
20
20
20
0
10
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
30
10
10
0
0
% F
% Gly:
0
0
10
0
0
0
20
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
20
20
10
10
0
20
20
20
10
0
10
% I
% Lys:
10
40
10
40
10
0
0
0
20
10
0
10
20
10
0
% K
% Leu:
10
0
10
20
0
0
30
10
0
0
10
10
0
10
0
% L
% Met:
0
10
0
0
10
10
10
10
10
0
0
0
0
0
30
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
30
0
0
0
10
0
20
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
30
0
0
0
0
10
0
0
10
20
10
% R
% Ser:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
20
% S
% Thr:
0
0
10
0
10
20
0
50
20
0
10
0
0
10
10
% T
% Val:
20
0
0
0
0
0
10
0
0
0
10
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _