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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRUNE
All Species:
17.88
Human Site:
S399
Identified Species:
43.7
UniProt:
Q86TP1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TP1
NP_067045.1
453
50200
S399
N
S
L
I
S
G
L
S
Q
D
E
E
D
P
P
Chimpanzee
Pan troglodytes
XP_001166177
321
35403
Q268
S
L
I
S
G
L
S
Q
D
E
E
D
P
P
L
Rhesus Macaque
Macaca mulatta
XP_001103486
453
50170
S399
N
S
L
I
S
G
L
S
Q
D
E
E
D
P
P
Dog
Lupus familis
XP_540307
547
59452
S493
N
S
L
V
P
G
L
S
Q
D
E
E
E
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW1
454
50221
S400
N
S
L
I
S
G
L
S
Q
D
E
E
D
P
P
Rat
Rattus norvegicus
Q6AYG3
454
49980
S400
N
S
L
I
A
G
L
S
Q
D
D
E
D
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518966
132
14358
H79
P
Q
L
A
A
L
L
H
G
T
I
V
L
D
C
Chicken
Gallus gallus
XP_424651
292
31086
G239
A
A
L
G
G
G
P
G
T
A
A
G
P
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001153766
447
49799
D394
D
Q
S
D
C
L
E
D
A
G
I
E
D
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476684
405
45161
R352
R
P
H
E
V
D
T
R
F
M
G
G
C
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.8
97.5
74.4
N.A.
85.4
85.2
N.A.
20.7
39.2
N.A.
48.7
N.A.
28.7
N.A.
N.A.
N.A.
Protein Similarity:
100
67.5
98.4
77.6
N.A.
90
90.3
N.A.
23.3
49.4
N.A.
67.7
N.A.
47.4
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
100
86.6
N.A.
13.3
13.3
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
93.3
N.A.
100
100
N.A.
20
20
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
20
0
0
0
10
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
10
0
0
10
0
10
0
10
10
50
10
10
50
20
0
% D
% Glu:
0
0
0
10
0
0
10
0
0
10
50
60
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
20
60
0
10
10
10
10
20
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
40
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
70
0
0
30
60
0
0
0
0
0
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
10
0
10
0
0
0
0
0
20
60
50
% P
% Gln:
0
20
0
0
0
0
0
10
50
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
50
10
10
30
0
10
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
10
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _