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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD3
All Species:
20
Human Site:
S450
Identified Species:
44
UniProt:
Q86TU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TU7
NP_115609.2
594
67257
S450
T
T
I
E
E
D
K
S
V
L
K
N
H
D
L
Chimpanzee
Pan troglodytes
XP_522946
594
67230
S450
T
T
I
E
E
D
K
S
V
L
K
N
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001103370
595
67455
S450
T
T
I
E
E
D
K
S
V
L
K
N
Q
D
L
Dog
Lupus familis
XP_547974
589
66391
S450
T
T
I
E
E
D
K
S
F
L
R
N
H
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WC0
594
67158
I450
T
T
I
E
E
D
K
I
V
L
K
N
P
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512656
355
39998
E231
A
I
K
L
R
L
G
E
K
E
I
L
E
K
A
Chicken
Gallus gallus
Q5ZML9
593
67177
S450
T
T
V
E
D
D
K
S
F
L
E
T
H
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956348
596
67232
S450
T
A
S
E
E
D
R
S
M
L
E
K
P
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393639
457
52653
N332
S
G
F
V
Y
M
E
N
K
Q
D
G
F
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798530
682
75899
E451
T
S
I
Q
E
D
E
E
K
L
K
D
G
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI84
482
54593
L358
Q
Y
L
R
L
V
A
L
G
G
P
D
A
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
90
N.A.
91.4
N.A.
N.A.
49.4
85.3
N.A.
70.6
N.A.
N.A.
32.4
N.A.
36.2
Protein Similarity:
100
99.8
99.5
94.7
N.A.
94.4
N.A.
N.A.
53.7
92.5
N.A.
84.7
N.A.
N.A.
47.6
N.A.
56.8
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
N.A.
N.A.
0
66.6
N.A.
53.3
N.A.
N.A.
6.6
N.A.
46.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
N.A.
N.A.
0
86.6
N.A.
73.3
N.A.
N.A.
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
73
0
0
0
0
10
19
0
64
0
% D
% Glu:
0
0
0
64
64
0
19
19
0
10
19
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
19
0
0
0
10
10
0
% F
% Gly:
0
10
0
0
0
0
10
0
10
10
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% H
% Ile:
0
10
55
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
55
0
28
0
46
10
0
19
0
% K
% Leu:
0
0
10
10
10
10
0
10
0
73
0
10
0
0
91
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
46
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
19
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
10
0
0
19
0
0
% Q
% Arg:
0
0
0
10
10
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
10
0
0
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
73
55
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
10
0
10
0
0
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _