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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD3
All Species:
28.18
Human Site:
Y288
Identified Species:
62
UniProt:
Q86TU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TU7
NP_115609.2
594
67257
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Chimpanzee
Pan troglodytes
XP_522946
594
67230
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Rhesus Macaque
Macaca mulatta
XP_001103370
595
67455
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Dog
Lupus familis
XP_547974
589
66391
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91WC0
594
67158
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512656
355
39998
R76
I
Y
I
F
Y
G
T
R
S
N
A
E
F
V
I
Chicken
Gallus gallus
Q5ZML9
593
67177
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956348
596
67232
Y288
N
G
L
I
T
T
G
Y
N
L
E
D
D
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393639
457
52653
D177
S
K
W
K
P
Y
L
D
I
L
P
T
T
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798530
682
75899
F288
N
G
E
M
K
T
D
F
I
E
E
R
D
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI84
482
54593
T203
D
L
F
S
S
R
I
T
L
D
D
F
I
W
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
90
N.A.
91.4
N.A.
N.A.
49.4
85.3
N.A.
70.6
N.A.
N.A.
32.4
N.A.
36.2
Protein Similarity:
100
99.8
99.5
94.7
N.A.
94.4
N.A.
N.A.
53.7
92.5
N.A.
84.7
N.A.
N.A.
47.6
N.A.
56.8
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
100
N.A.
100
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
20
100
N.A.
100
N.A.
N.A.
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
73
% C
% Asp:
10
0
0
0
0
0
10
10
0
10
10
64
73
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
73
10
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
10
0
0
0
10
10
0
0
% F
% Gly:
0
73
0
0
0
10
64
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
64
0
0
10
0
19
0
0
0
10
0
10
% I
% Lys:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
64
0
0
0
10
0
10
73
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
0
0
0
0
0
0
0
64
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
0
10
0
64
0
% R
% Ser:
10
0
0
10
10
0
0
0
10
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
64
73
10
10
0
0
0
10
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
10
0
0
10
10
0
64
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _