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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC7B
All Species:
25.15
Human Site:
S673
Identified Species:
50.3
UniProt:
Q86TV6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TV6
NP_001010854.1
843
94179
S673
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Chimpanzee
Pan troglodytes
XP_510118
843
94150
S673
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Rhesus Macaque
Macaca mulatta
XP_001090821
801
89303
S639
E
V
A
S
S
L
Q
S
S
A
P
K
Q
G
P
Dog
Lupus familis
XP_537538
1069
117658
S899
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGB2
858
96138
A688
A
A
S
R
L
E
E
A
M
S
E
L
T
L
T
Rat
Rattus norvegicus
NP_001102189
585
64878
S423
E
V
A
S
S
L
Q
S
S
A
P
K
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506427
843
94241
S673
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Chicken
Gallus gallus
NP_001006484
792
89090
S630
S
D
S
G
R
G
S
S
L
L
D
R
A
I
A
Frog
Xenopus laevis
NP_001090571
843
94707
S673
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Zebra Danio
Brachydanio rerio
NP_001074072
844
94521
S674
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624273
818
92931
F656
V
A
S
S
L
S
S
F
T
P
K
P
G
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784188
844
94184
E675
R
V
E
H
A
L
S
E
V
A
S
S
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.9
75.6
N.A.
51
67.9
N.A.
95
87.4
89
83.1
N.A.
N.A.
39.6
N.A.
45.7
Protein Similarity:
100
99.6
94.9
77.8
N.A.
71.2
69
N.A.
98
91.6
95.6
92.7
N.A.
N.A.
60.2
N.A.
65.6
P-Site Identity:
100
100
6.6
100
N.A.
6.6
6.6
N.A.
100
13.3
100
100
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
26.6
6.6
N.A.
100
40
100
100
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
9
50
0
9
0
25
50
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
17
0
9
50
0
9
9
9
50
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
0
0
0
0
0
0
9
25
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% K
% Leu:
0
0
0
0
17
25
50
0
9
9
0
9
0
59
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
17
9
0
9
17
% P
% Gln:
0
0
0
0
50
0
17
0
0
0
0
0
17
0
59
% Q
% Arg:
9
50
0
9
9
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
59
0
25
25
17
9
25
75
17
9
9
59
59
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% T
% Val:
9
25
50
0
0
0
0
0
9
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _