KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC7B
All Species:
8.79
Human Site:
T457
Identified Species:
17.58
UniProt:
Q86TV6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TV6
NP_001010854.1
843
94179
T457
E
A
E
K
F
A
K
T
V
V
D
V
G
E
K
Chimpanzee
Pan troglodytes
XP_510118
843
94150
T457
E
A
E
K
F
A
K
T
V
V
D
V
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001090821
801
89303
K429
K
T
S
E
F
K
A
K
G
Y
L
A
L
G
L
Dog
Lupus familis
XP_537538
1069
117658
T683
E
A
E
K
F
A
K
T
V
V
D
A
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGB2
858
96138
V475
E
A
E
H
F
A
T
V
V
I
G
L
G
E
E
Rat
Rattus norvegicus
NP_001102189
585
64878
K213
K
T
S
E
F
K
A
K
G
Y
L
A
L
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506427
843
94241
A457
E
A
E
S
F
A
K
A
V
V
D
A
G
E
K
Chicken
Gallus gallus
NP_001006484
792
89090
L420
S
A
R
A
V
K
V
L
K
E
C
I
R
L
K
Frog
Xenopus laevis
NP_001090571
843
94707
M457
E
A
E
R
F
A
K
M
V
V
D
C
G
E
K
Zebra Danio
Brachydanio rerio
NP_001074072
844
94521
I458
E
G
E
R
F
A
K
I
V
I
D
M
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624273
818
92931
Q446
T
S
N
S
Q
G
M
Q
S
R
C
H
L
Y
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784188
844
94184
K461
E
G
L
E
F
A
S
K
A
V
E
V
G
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.9
75.6
N.A.
51
67.9
N.A.
95
87.4
89
83.1
N.A.
N.A.
39.6
N.A.
45.7
Protein Similarity:
100
99.6
94.9
77.8
N.A.
71.2
69
N.A.
98
91.6
95.6
92.7
N.A.
N.A.
60.2
N.A.
65.6
P-Site Identity:
100
100
6.6
93.3
N.A.
53.3
6.6
N.A.
80
13.3
80
66.6
N.A.
N.A.
0
N.A.
40
P-Site Similarity:
100
100
20
93.3
N.A.
73.3
20
N.A.
80
20
86.6
86.6
N.A.
N.A.
6.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
9
0
67
17
9
9
0
0
34
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
67
0
59
25
0
0
0
0
0
9
9
0
0
59
9
% E
% Phe:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
9
0
0
17
0
9
0
67
17
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
17
0
9
0
0
9
% I
% Lys:
17
0
0
25
0
25
50
25
9
0
0
0
0
9
59
% K
% Leu:
0
0
9
0
0
0
0
9
0
0
17
9
25
9
17
% L
% Met:
0
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
9
17
0
0
0
0
0
9
0
0
9
0
0
% R
% Ser:
9
9
17
17
0
0
9
0
9
0
0
0
0
0
0
% S
% Thr:
9
17
0
0
0
0
9
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
9
9
59
50
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _