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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK1
All Species:
1.21
Human Site:
S74
Identified Species:
2.05
UniProt:
Q86TW2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TW2
NP_065154.2
530
60577
S74
Y
L
Q
L
R
S
K
S
W
P
V
F
L
Q
V
Chimpanzee
Pan troglodytes
XP_510098
657
73866
V208
Y
L
Q
L
R
S
K
V
H
L
R
S
A
R
R
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
V74
Y
L
Q
L
R
S
K
V
H
L
R
S
A
R
R
Dog
Lupus familis
XP_547933
767
85798
Y311
V
P
Y
G
S
E
E
Y
L
Q
L
R
S
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0L4
525
59717
V74
Y
L
Q
R
R
S
Q
V
H
L
R
S
A
R
R
Rat
Rattus norvegicus
NP_001102455
455
51692
I74
Y
L
Q
R
R
S
Q
I
H
D
L
F
L
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505392
386
43627
V23
G
A
A
S
L
A
Q
V
H
K
A
V
L
H
D
Chicken
Gallus gallus
Q5ZMT7
519
59182
V71
Y
D
F
L
K
S
Q
V
H
L
R
S
A
E
R
Frog
Xenopus laevis
Q6INL7
520
59525
V74
Y
E
N
I
K
S
Q
V
H
L
R
S
A
H
R
Zebra Danio
Brachydanio rerio
NP_001116521
521
59695
V73
Y
W
A
V
K
S
K
V
H
R
R
S
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611947
518
59841
V75
Y
K
A
E
K
S
R
V
H
K
I
A
A
E
K
Honey Bee
Apis mellifera
XP_392396
516
58880
V76
Y
V
D
L
K
S
K
V
H
K
Y
G
A
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
R77
L
A
E
G
S
S
E
R
A
K
V
K
H
E
V
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
R97
S
Y
E
N
K
K
E
R
E
V
A
L
N
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
97.1
58.1
N.A.
87.3
74.1
N.A.
54.7
75.2
62.6
69
N.A.
44.7
45.8
N.A.
N.A.
Protein Similarity:
100
79.5
98.1
63
N.A.
93
80.1
N.A.
63.4
87.7
79.4
81.1
N.A.
65.4
64.3
N.A.
N.A.
P-Site Identity:
100
46.6
46.6
6.6
N.A.
33.3
46.6
N.A.
6.6
20
13.3
20
N.A.
13.3
33.3
N.A.
N.A.
P-Site Similarity:
100
53.3
53.3
26.6
N.A.
46.6
60
N.A.
20
40
33.3
40
N.A.
40
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
22
0
0
8
0
0
8
0
15
8
58
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
8
0
0
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
8
15
8
0
8
22
0
8
0
0
0
0
29
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
15
0
0
8
% F
% Gly:
8
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
72
0
0
0
8
15
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
43
8
36
0
0
29
0
8
0
15
15
% K
% Leu:
8
36
0
36
8
0
0
0
8
36
15
8
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
36
0
0
0
36
0
0
8
0
0
0
15
0
% Q
% Arg:
0
0
0
15
36
0
8
15
0
8
43
8
0
22
43
% R
% Ser:
8
0
0
8
15
79
0
8
0
0
0
43
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
8
0
0
0
65
0
8
15
8
0
0
22
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
72
8
8
0
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _