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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK1 All Species: 16.36
Human Site: T487 Identified Species: 27.69
UniProt: Q86TW2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TW2 NP_065154.2 530 60577 T487 T C S F F R R T Q I S F S E A
Chimpanzee Pan troglodytes XP_510098 657 73866 T614 T C S F F R R T Q I S F S E A
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 T480 T C S F F R R T Q I S F R E A
Dog Lupus familis XP_547933 767 85798 T724 A S S F F R R T Q I S F R E A
Cat Felis silvestris
Mouse Mus musculus Q9D0L4 525 59717 T480 A G S F F R R T Q I S F S E A
Rat Rattus norvegicus NP_001102455 455 51692 W442 K A L R L A C W V S A L L G W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505392 386 43627 I374 G S W L G N C I I V L L S W L
Chicken Gallus gallus Q5ZMT7 519 59182 V477 S H S L Y R R V H I S L T E A
Frog Xenopus laevis Q6INL7 520 59525 I480 A D S L W S Y I H I S L S E T
Zebra Danio Brachydanio rerio NP_001116521 521 59695 V479 A S S R S R R V R I W L S E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611947 518 59841 R481 Q S D S G S S R I L W L R V R
Honey Bee Apis mellifera XP_392396 516 58880 W480 C T N V W E K W K I S L S K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 L507 K K S L M K W L K V W F E G F
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 W527 I N S E Y A R W S I K W M W E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 97.1 58.1 N.A. 87.3 74.1 N.A. 54.7 75.2 62.6 69 N.A. 44.7 45.8 N.A. N.A.
Protein Similarity: 100 79.5 98.1 63 N.A. 93 80.1 N.A. 63.4 87.7 79.4 81.1 N.A. 65.4 64.3 N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 86.6 0 N.A. 6.6 46.6 33.3 40 N.A. 0 20 N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 86.6 6.6 N.A. 13.3 66.6 40 46.6 N.A. 6.6 53.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.8 30 N.A.
Protein Similarity: N.A. N.A. N.A. 58.7 49 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 8 0 0 0 15 0 0 0 0 8 0 0 0 43 % A
% Cys: 8 22 0 0 0 0 15 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 8 0 0 0 0 0 0 8 58 8 % E
% Phe: 0 0 0 36 36 0 0 0 0 0 0 43 0 0 8 % F
% Gly: 8 8 0 0 15 0 0 0 0 0 0 0 0 15 0 % G
% His: 0 8 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 15 15 72 0 0 0 0 0 % I
% Lys: 15 8 0 0 0 8 8 0 15 0 8 0 0 8 0 % K
% Leu: 0 0 8 29 8 0 0 8 0 8 8 50 8 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 8 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 36 0 0 0 0 0 8 % Q
% Arg: 0 0 0 15 0 50 58 8 8 0 0 0 22 0 15 % R
% Ser: 8 29 72 8 8 15 8 0 8 8 58 0 50 0 0 % S
% Thr: 22 8 0 0 0 0 0 36 0 0 0 0 8 0 8 % T
% Val: 0 0 0 8 0 0 0 15 8 15 0 0 0 8 0 % V
% Trp: 0 0 8 0 15 0 8 22 0 0 22 8 0 15 8 % W
% Tyr: 0 0 0 0 15 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _