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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT1
All Species:
15.15
Human Site:
S298
Identified Species:
37.04
UniProt:
Q86TX2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TX2
NP_001032238.1
421
46277
S298
D
I
V
D
V
L
N
S
P
L
E
G
P
D
Q
Chimpanzee
Pan troglodytes
XP_510048
483
53239
S360
D
I
V
D
V
L
N
S
P
L
E
G
P
D
Q
Rhesus Macaque
Macaca mulatta
XP_001091182
421
46346
D298
D
I
V
D
I
R
N
D
L
V
G
G
Y
E
N
Dog
Lupus familis
XP_547892
445
48428
S329
D
I
L
D
V
L
N
S
P
L
E
G
A
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYR7
432
47471
N309
D
I
V
D
L
L
N
N
P
L
E
G
P
D
Q
Rat
Rattus norvegicus
O88267
419
45995
S298
D
V
V
D
A
L
Q
S
P
L
V
E
Q
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520078
421
46050
S298
D
I
V
D
V
L
N
S
P
L
E
E
P
D
T
Chicken
Gallus gallus
XP_426429
461
50969
D346
D
Y
S
D
I
A
F
D
P
F
K
A
P
G
N
Frog
Xenopus laevis
NP_001084617
428
46458
N314
D
I
S
N
V
L
N
N
P
L
E
E
P
N
R
Zebra Danio
Brachydanio rerio
XP_696711
513
56999
D390
D
I
G
E
V
M
D
D
P
M
S
K
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.3
70.7
79.3
N.A.
75
76.7
N.A.
71.2
49.6
57
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.7
80.7
84.4
N.A.
85.4
85.9
N.A.
82.1
62
73.3
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
86.6
N.A.
86.6
46.6
N.A.
86.6
26.6
60
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
93.3
N.A.
100
53.3
N.A.
86.6
40
86.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
80
0
0
10
30
0
0
0
0
0
50
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
60
30
10
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
50
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
80
0
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% K
% Leu:
0
0
10
0
10
70
0
0
10
70
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
70
20
0
0
0
0
0
10
20
% N
% Pro:
0
0
0
0
0
0
0
0
90
0
0
0
60
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
40
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
20
0
0
0
0
50
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
60
0
60
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _