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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA2
All Species:
29.09
Human Site:
S130
Identified Species:
49.23
UniProt:
Q86U28
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U28
NP_919255.2
154
16476
S130
F
S
Q
E
L
I
R
S
S
F
Q
V
L
N
N
Chimpanzee
Pan troglodytes
XP_001143075
195
21038
S171
F
S
Q
E
L
I
R
S
S
F
Q
V
L
N
N
Rhesus Macaque
Macaca mulatta
XP_001094302
154
16440
S130
F
S
Q
E
L
I
R
S
S
F
Q
V
L
N
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCB8
154
16699
S130
F
S
Q
E
L
I
R
S
S
F
Q
V
L
N
N
Rat
Rattus norvegicus
NP_001102748
154
16661
S130
F
S
Q
E
L
I
R
S
S
F
Q
V
L
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421267
187
20319
S146
F
S
Q
E
L
I
R
S
S
F
Q
V
M
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922511
155
16837
A131
F
S
Q
E
L
I
R
A
S
F
Q
V
L
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651267
139
15228
G116
H
S
E
L
I
R
A
G
F
R
M
V
A
N
P
Honey Bee
Apis mellifera
XP_001120329
157
17588
S133
F
H
T
E
L
I
R
S
A
F
R
I
T
N
N
Nematode Worm
Caenorhab. elegans
NP_496981
134
14840
F111
E
D
L
M
K
S
S
F
R
I
V
N
N
P
I
Sea Urchin
Strong. purpuratus
XP_783841
135
14758
A112
H
E
E
L
I
R
S
A
F
S
V
I
D
N
P
Poplar Tree
Populus trichocarpa
XP_002308154
153
16947
A129
Y
V
E
E
L
I
R
A
A
F
I
V
A
T
N
Maize
Zea mays
NP_001151226
158
17226
S135
Y
E
E
E
L
I
R
S
T
F
V
V
S
T
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCY2
158
17395
A134
Y
E
E
E
L
I
R
A
A
F
V
V
A
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.4
N.A.
N.A.
83.7
83.7
N.A.
N.A.
53.4
N.A.
52.2
N.A.
46.7
47.1
43.5
47.4
Protein Similarity:
100
78.4
97.4
N.A.
N.A.
86.3
86.3
N.A.
N.A.
62.5
N.A.
66.4
N.A.
62.3
64.9
64.2
68.1
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
80
N.A.
86.6
N.A.
20
60
0
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
86.6
N.A.
93.3
N.A.
33.3
80
0
33.3
Percent
Protein Identity:
50
44.9
N.A.
41.7
N.A.
N.A.
Protein Similarity:
62.3
58.8
N.A.
60.1
N.A.
N.A.
P-Site Identity:
46.6
53.3
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
73.3
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
29
22
0
0
0
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
22
36
79
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
58
0
0
0
0
0
0
8
15
79
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
79
0
0
0
8
8
15
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
15
79
0
0
0
0
0
0
0
43
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
8
58
72
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
22
% P
% Gln:
0
0
50
0
0
0
0
0
0
0
50
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
79
0
8
8
8
0
0
0
0
% R
% Ser:
0
58
0
0
0
8
15
58
50
8
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
0
0
0
8
15
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
29
79
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _