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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA2
All Species:
18.79
Human Site:
S41
Identified Species:
31.79
UniProt:
Q86U28
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U28
NP_919255.2
154
16476
S41
A
R
R
E
A
S
S
S
S
P
E
A
G
E
G
Chimpanzee
Pan troglodytes
XP_001143075
195
21038
S82
A
R
R
E
A
S
S
S
S
P
E
A
G
E
G
Rhesus Macaque
Macaca mulatta
XP_001094302
154
16440
S41
A
R
R
E
A
S
S
S
S
P
E
A
G
E
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCB8
154
16699
S41
T
R
W
E
T
T
S
S
I
P
E
A
G
E
G
Rat
Rattus norvegicus
NP_001102748
154
16661
S41
T
R
W
E
T
T
S
S
I
P
E
A
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421267
187
20319
T57
S
S
S
Q
P
G
P
T
E
S
D
S
S
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922511
155
16837
Q42
T
S
S
N
T
E
H
Q
N
T
S
S
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651267
139
15228
E32
A
S
T
S
A
N
P
E
L
S
V
Q
V
S
E
Honey Bee
Apis mellifera
XP_001120329
157
17588
D44
L
L
N
N
T
L
I
D
S
T
V
K
D
K
N
Nematode Worm
Caenorhab. elegans
NP_496981
134
14840
I27
R
M
L
T
E
Q
E
I
K
V
T
N
K
A
A
Sea Urchin
Strong. purpuratus
XP_783841
135
14758
Q28
A
E
A
Q
E
S
T
Q
P
E
L
K
L
S
D
Poplar Tree
Populus trichocarpa
XP_002308154
153
16947
D42
E
A
S
T
L
V
D
D
S
I
H
L
T
D
N
Maize
Zea mays
NP_001151226
158
17226
E46
R
A
S
Q
L
P
A
E
A
Q
A
V
R
M
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCY2
158
17395
S45
S
S
S
S
Q
P
E
S
S
S
N
D
V
V
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.4
N.A.
N.A.
83.7
83.7
N.A.
N.A.
53.4
N.A.
52.2
N.A.
46.7
47.1
43.5
47.4
Protein Similarity:
100
78.4
97.4
N.A.
N.A.
86.3
86.3
N.A.
N.A.
62.5
N.A.
66.4
N.A.
62.3
64.9
64.2
68.1
P-Site Identity:
100
100
100
N.A.
N.A.
66.6
66.6
N.A.
N.A.
13.3
N.A.
0
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
73.3
73.3
N.A.
N.A.
46.6
N.A.
20
N.A.
20
13.3
0
26.6
Percent
Protein Identity:
50
44.9
N.A.
41.7
N.A.
N.A.
Protein Similarity:
62.3
58.8
N.A.
60.1
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
15
8
0
29
0
8
0
8
0
8
36
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
15
0
0
8
8
8
15
8
% D
% Glu:
8
8
0
36
15
8
15
15
8
8
36
0
0
43
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
36
0
43
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
8
15
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
15
8
8
0
% K
% Leu:
8
8
8
0
15
8
0
0
8
0
8
8
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
15
0
8
0
0
8
0
8
8
0
0
15
% N
% Pro:
0
0
0
0
8
15
15
0
8
36
0
0
0
0
0
% P
% Gln:
0
0
0
22
8
8
0
15
0
8
0
8
0
0
0
% Q
% Arg:
15
36
22
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
15
29
36
15
0
29
36
43
43
22
8
15
8
15
0
% S
% Thr:
22
0
8
15
29
15
8
8
0
15
8
0
15
0
8
% T
% Val:
0
0
0
0
0
8
0
0
0
8
15
8
15
8
0
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _