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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA2
All Species:
10
Human Site:
T18
Identified Species:
16.92
UniProt:
Q86U28
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U28
NP_919255.2
154
16476
T18
A
A
T
Q
R
A
V
T
P
W
P
R
G
R
L
Chimpanzee
Pan troglodytes
XP_001143075
195
21038
T59
A
A
T
Q
R
A
V
T
P
W
P
R
G
R
L
Rhesus Macaque
Macaca mulatta
XP_001094302
154
16440
T18
A
A
T
Q
R
A
V
T
P
W
P
R
G
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCB8
154
16699
I18
A
E
A
V
R
A
V
I
P
R
R
S
G
R
L
Rat
Rattus norvegicus
NP_001102748
154
16661
I18
A
E
A
F
G
A
A
I
P
R
R
Q
G
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421267
187
20319
P34
G
R
A
P
L
G
P
P
P
A
A
A
C
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922511
155
16837
L19
P
K
T
A
S
F
H
L
L
N
L
L
S
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651267
139
15228
A9
A
F
L
L
R
Q
V
A
R
S
G
L
Q
R
N
Honey Bee
Apis mellifera
XP_001120329
157
17588
F21
N
F
V
A
N
R
Y
F
S
R
L
L
T
S
Q
Nematode Worm
Caenorhab. elegans
NP_496981
134
14840
Sea Urchin
Strong. purpuratus
XP_783841
135
14758
Poplar Tree
Populus trichocarpa
XP_002308154
153
16947
S19
R
V
T
P
L
F
T
S
W
I
R
Q
N
H
R
Maize
Zea mays
NP_001151226
158
17226
A23
L
A
R
G
R
L
R
A
N
H
R
M
L
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCY2
158
17395
R22
G
R
I
R
E
N
H
R
L
L
N
F
S
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.4
N.A.
N.A.
83.7
83.7
N.A.
N.A.
53.4
N.A.
52.2
N.A.
46.7
47.1
43.5
47.4
Protein Similarity:
100
78.4
97.4
N.A.
N.A.
86.3
86.3
N.A.
N.A.
62.5
N.A.
66.4
N.A.
62.3
64.9
64.2
68.1
P-Site Identity:
100
100
100
N.A.
N.A.
53.3
40
N.A.
N.A.
13.3
N.A.
6.6
N.A.
26.6
0
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
53.3
46.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
26.6
0
0
0
Percent
Protein Identity:
50
44.9
N.A.
41.7
N.A.
N.A.
Protein Similarity:
62.3
58.8
N.A.
60.1
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
29
22
15
0
36
8
15
0
8
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
15
0
8
0
15
0
8
0
0
0
8
0
0
0
% F
% Gly:
15
0
0
8
8
8
0
0
0
0
8
0
36
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
15
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
15
8
0
8
15
8
15
22
8
0
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
8
8
0
0
8
8
8
0
8
0
8
% N
% Pro:
8
0
0
15
0
0
8
8
43
0
22
0
0
0
0
% P
% Gln:
0
0
0
22
0
8
0
0
0
0
0
15
8
0
8
% Q
% Arg:
8
15
8
8
43
8
8
8
8
22
29
22
0
43
15
% R
% Ser:
0
0
0
0
8
0
0
8
8
8
0
8
15
22
8
% S
% Thr:
0
0
36
0
0
0
8
22
0
0
0
0
8
0
0
% T
% Val:
0
8
8
8
0
0
36
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
22
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _