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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA2
All Species:
3.64
Human Site:
T27
Identified Species:
6.15
UniProt:
Q86U28
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U28
NP_919255.2
154
16476
T27
W
P
R
G
R
L
L
T
A
S
L
G
P
Q
A
Chimpanzee
Pan troglodytes
XP_001143075
195
21038
A68
W
P
R
G
R
L
L
A
A
S
L
G
P
Q
A
Rhesus Macaque
Macaca mulatta
XP_001094302
154
16440
A27
W
P
R
G
R
L
L
A
A
S
L
G
L
Q
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCB8
154
16699
A27
R
R
S
G
R
L
L
A
V
F
P
R
L
L
T
Rat
Rattus norvegicus
NP_001102748
154
16661
A27
R
R
Q
G
R
L
L
A
A
F
P
R
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421267
187
20319
R43
A
A
A
C
A
L
G
R
S
L
R
W
A
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922511
155
16837
C28
N
L
L
S
V
R
S
C
A
A
P
L
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651267
139
15228
I18
S
G
L
Q
R
N
L
I
L
M
R
H
A
T
A
Honey Bee
Apis mellifera
XP_001120329
157
17588
Y30
R
L
L
T
S
Q
W
Y
N
T
S
T
V
S
L
Nematode Worm
Caenorhab. elegans
NP_496981
134
14840
T13
I
G
R
L
M
A
C
T
V
T
R
Q
A
H
R
Sea Urchin
Strong. purpuratus
XP_783841
135
14758
T14
A
P
T
T
G
S
K
T
Q
L
M
S
T
G
A
Poplar Tree
Populus trichocarpa
XP_002308154
153
16947
L28
I
R
Q
N
H
R
L
L
S
S
S
A
L
R
E
Maize
Zea mays
NP_001151226
158
17226
S32
H
R
M
L
S
S
A
S
S
T
A
A
I
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCY2
158
17395
A31
L
N
F
S
S
A
S
A
I
K
E
A
S
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.4
N.A.
N.A.
83.7
83.7
N.A.
N.A.
53.4
N.A.
52.2
N.A.
46.7
47.1
43.5
47.4
Protein Similarity:
100
78.4
97.4
N.A.
N.A.
86.3
86.3
N.A.
N.A.
62.5
N.A.
66.4
N.A.
62.3
64.9
64.2
68.1
P-Site Identity:
100
93.3
86.6
N.A.
N.A.
26.6
33.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
20
0
13.3
20
P-Site Similarity:
100
93.3
86.6
N.A.
N.A.
26.6
40
N.A.
N.A.
20
N.A.
13.3
N.A.
20
6.6
20
26.6
Percent
Protein Identity:
50
44.9
N.A.
41.7
N.A.
N.A.
Protein Similarity:
62.3
58.8
N.A.
60.1
N.A.
N.A.
P-Site Identity:
13.3
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
26.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
0
8
15
8
36
36
8
8
22
22
0
36
% A
% Cys:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
0
15
0
36
8
0
8
0
0
0
0
22
0
8
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
15
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% K
% Leu:
8
15
22
15
0
43
50
8
8
15
22
8
29
15
8
% L
% Met:
0
0
8
0
8
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
8
8
0
8
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
29
0
0
0
0
0
0
0
0
22
0
15
0
0
% P
% Gln:
0
0
15
8
0
8
0
0
8
0
0
8
0
22
0
% Q
% Arg:
22
29
29
0
43
15
0
8
0
0
22
15
0
8
15
% R
% Ser:
8
0
8
15
22
15
15
8
22
29
15
8
8
29
15
% S
% Thr:
0
0
8
15
0
0
0
22
0
22
0
8
15
8
22
% T
% Val:
0
0
0
0
8
0
0
0
15
0
0
0
8
0
0
% V
% Trp:
22
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _