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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA2
All Species:
28.79
Human Site:
T53
Identified Species:
48.72
UniProt:
Q86U28
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U28
NP_919255.2
154
16476
T53
G
E
G
Q
I
R
L
T
D
S
C
V
Q
R
L
Chimpanzee
Pan troglodytes
XP_001143075
195
21038
T94
G
E
G
Q
I
R
L
T
D
S
C
V
Q
R
L
Rhesus Macaque
Macaca mulatta
XP_001094302
154
16440
T53
G
E
G
Q
I
R
L
T
D
S
C
V
Q
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCB8
154
16699
T53
G
E
G
Q
I
R
L
T
D
S
C
V
Q
R
L
Rat
Rattus norvegicus
NP_001102748
154
16661
T53
G
E
G
Q
I
R
L
T
D
S
C
V
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421267
187
20319
S69
S
E
G
Q
V
Y
L
S
E
S
C
V
K
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922511
155
16837
S54
T
D
A
E
V
H
L
S
Q
S
C
V
K
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651267
139
15228
R44
V
S
E
S
C
L
K
R
L
R
E
I
C
V
D
Honey Bee
Apis mellifera
XP_001120329
157
17588
T56
D
K
N
D
I
I
I
T
D
S
C
V
K
R
L
Nematode Worm
Caenorhab. elegans
NP_496981
134
14840
E39
K
A
A
S
R
L
K
E
V
V
D
N
G
E
R
Sea Urchin
Strong. purpuratus
XP_783841
135
14758
Q40
L
S
D
S
C
V
K
Q
L
H
K
L
G
E
D
Poplar Tree
Populus trichocarpa
XP_002308154
153
16947
L54
T
D
N
C
I
R
R
L
K
E
L
Q
T
S
E
Maize
Zea mays
NP_001151226
158
17226
R58
R
M
T
E
G
C
V
R
R
L
K
E
L
H
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCY2
158
17395
C57
V
V
H
L
S
D
N
C
I
R
R
M
K
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.4
N.A.
N.A.
83.7
83.7
N.A.
N.A.
53.4
N.A.
52.2
N.A.
46.7
47.1
43.5
47.4
Protein Similarity:
100
78.4
97.4
N.A.
N.A.
86.3
86.3
N.A.
N.A.
62.5
N.A.
66.4
N.A.
62.3
64.9
64.2
68.1
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
60
N.A.
40
N.A.
0
53.3
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
86.6
N.A.
73.3
N.A.
6.6
73.3
0
6.6
Percent
Protein Identity:
50
44.9
N.A.
41.7
N.A.
N.A.
Protein Similarity:
62.3
58.8
N.A.
60.1
N.A.
N.A.
P-Site Identity:
13.3
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
15
8
0
8
0
0
58
0
8
0
0
% C
% Asp:
8
15
8
8
0
8
0
0
43
0
8
0
0
0
15
% D
% Glu:
0
43
8
15
0
0
0
8
8
8
8
8
0
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
36
0
43
0
8
0
0
0
0
0
0
0
15
0
0
% G
% His:
0
0
8
0
0
8
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
50
8
8
0
8
0
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
22
0
8
0
15
0
29
0
0
% K
% Leu:
8
0
0
8
0
15
50
8
15
8
8
8
8
0
65
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
43
0
0
0
8
8
0
0
8
36
0
0
% Q
% Arg:
8
0
0
0
8
43
8
15
8
15
8
0
0
58
8
% R
% Ser:
8
15
0
22
8
0
0
15
0
58
0
0
0
8
0
% S
% Thr:
15
0
8
0
0
0
0
43
0
0
0
0
8
0
0
% T
% Val:
15
8
0
0
15
8
8
0
8
8
0
58
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _