KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C14orf21
All Species:
21.82
Human Site:
S221
Identified Species:
60
UniProt:
Q86U38
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U38
NP_777573.1
636
69438
S221
L
G
G
T
I
L
E
S
E
R
A
R
P
R
G
Chimpanzee
Pan troglodytes
XP_522808
634
69046
S219
L
G
G
T
I
L
E
S
E
R
A
R
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001113913
637
69729
S222
L
G
G
T
I
L
E
S
E
R
A
R
P
R
G
Dog
Lupus familis
XP_850548
637
69328
S222
L
G
G
T
L
L
E
S
E
R
A
R
H
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMC4
636
70028
S221
L
G
G
T
L
L
E
S
E
R
G
K
P
R
G
Rat
Rattus norvegicus
NP_001099510
634
69684
S219
L
G
G
T
L
L
E
S
E
R
V
K
P
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080035
621
70138
Q220
L
G
G
T
V
L
S
Q
N
T
G
R
K
A
A
Zebra Danio
Brachydanio rerio
XP_002662124
604
66858
A208
V
E
T
T
A
P
H
A
K
K
D
R
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610276
665
75717
K224
L
V
G
M
H
V
P
K
I
A
F
E
K
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.3
86.6
N.A.
82
82.2
N.A.
N.A.
N.A.
46.5
34.9
N.A.
23
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97.3
92.3
N.A.
88.6
88.6
N.A.
N.A.
N.A.
65.7
52.9
N.A.
41.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
N.A.
40
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
46.6
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
12
0
12
45
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
67
0
67
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
78
89
0
0
0
0
0
0
0
23
0
0
12
78
% G
% His:
0
0
0
0
12
0
12
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
34
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
12
0
23
34
0
12
% K
% Leu:
89
0
0
0
34
78
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
12
0
0
0
0
0
56
0
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
67
0
67
0
67
0
% R
% Ser:
0
0
0
0
0
0
12
67
0
0
0
0
0
12
0
% S
% Thr:
0
0
12
89
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
12
12
0
0
12
12
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _