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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPN1 All Species: 15.45
Human Site: S286 Identified Species: 28.33
UniProt: Q86U42 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U42 NP_004634.1 306 32749 S286 R F Y S G F N S R P R G R V Y
Chimpanzee Pan troglodytes XP_509852 296 31478 N272 R Y R A R T T N Y N S S R S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_858764 333 37180 S313 R F Y S G F N S R P R G R V Y
Cat Felis silvestris
Mouse Mus musculus Q8CCS6 302 32278 S282 R F Y S G F N S R P R G R I Y
Rat Rattus norvegicus B0BNE4 269 29843 R249 G S L Q R K P R L R P H G Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520509 318 35286 S298 R F Y S G F N S R P R G R V Y
Chicken Gallus gallus XP_001232211 249 27885 V229 G Y Y G G Q P V R L R G R T Y
Frog Xenopus laevis Q7ZXB8 295 32194 R276 F Y S G Y T P R P R G R V Y R
Zebra Danio Brachydanio rerio NP_001098602 232 25663 P212 Y Y S G Y T P P R G R G R A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KNF2 224 24959 T204 S R A C C H S T F R G A R R A
Honey Bee Apis mellifera XP_393066 228 25717 Y208 G I I R G S A Y F G Y R P I R
Nematode Worm Caenorhab. elegans Q09295 191 21008 Y172 T V V V K Y V Y V N G P N R G
Sea Urchin Strong. purpuratus XP_799120 247 26565 G216 S P F G G G G G G G G Y G G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 N.A. 64.5 N.A. 96.7 38.2 N.A. 65.4 45.4 69.6 62 N.A. 45.7 46.4 25.1 45.4
Protein Similarity: 100 96.4 N.A. 68.7 N.A. 97.7 49.6 N.A. 69.5 56.2 75.8 68.9 N.A. 54.9 58.8 35.6 54.5
P-Site Identity: 100 13.3 N.A. 100 N.A. 93.3 0 N.A. 100 46.6 0 26.6 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 33.3 N.A. 100 N.A. 100 0 N.A. 100 53.3 6.6 40 N.A. 20 13.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 8 0 0 0 0 8 0 8 8 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 31 8 0 0 31 0 0 16 0 0 0 0 0 8 % F
% Gly: 24 0 0 31 54 8 8 8 8 24 31 47 16 8 16 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 0 0 0 16 0 % I
% Lys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 8 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 31 8 0 16 0 0 8 0 0 % N
% Pro: 0 8 0 0 0 0 31 8 8 31 8 8 8 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 0 8 0 % Q
% Arg: 39 8 8 8 16 0 0 16 47 24 47 16 62 16 24 % R
% Ser: 16 8 16 31 0 8 8 31 0 0 8 8 0 8 8 % S
% Thr: 8 0 0 0 0 24 8 8 0 0 0 0 0 8 0 % T
% Val: 0 8 8 8 0 0 8 8 8 0 0 0 8 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 31 39 0 16 8 0 16 8 0 8 8 0 8 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _