Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YRDC All Species: 17.27
Human Site: S21 Identified Species: 29.23
UniProt: Q86U90 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U90 NP_078916.3 279 29328 S21 V A A S V G L S E G P A G S R
Chimpanzee Pan troglodytes XP_513328 279 29381 S21 V A A S V G L S E G P A G S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539586 274 28633 S21 V A A G A G L S E G P A G S A
Cat Felis silvestris
Mouse Mus musculus Q3U5F4 280 29435 S21 V A A G M G L S D G P A S S G
Rat Rattus norvegicus Q499R4 280 29212 S21 V A A G M G L S D G P A G S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511974 148 15850
Chicken Gallus gallus XP_417757 255 26969 G21 R V A E G L P G P G H A R S S
Frog Xenopus laevis NP_001082498 236 25547
Zebra Danio Brachydanio rerio NP_001077336 235 25902
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027444 248 27575 H15 L Y R L L R A H H T S S R M Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793502 222 24027
Poplar Tree Populus trichocarpa XP_002313460 232 24943
Maize Zea mays NP_001148954 275 29299 R21 L V C A P S T R Q P L A R S F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974970 288 31285 S28 P L L R K G V S E L R C F S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 84.2 N.A. 85.3 86 N.A. 39.4 61.6 53 50.1 N.A. 39.4 N.A. N.A. 41.2
Protein Similarity: 100 99.6 N.A. 89.2 N.A. 89.2 90.3 N.A. 44.7 73.4 66.3 64.1 N.A. 58.4 N.A. N.A. 55.2
P-Site Identity: 100 100 N.A. 80 N.A. 66.6 73.3 N.A. 0 26.6 0 0 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 80 N.A. 80 86.6 N.A. 0 26.6 0 0 N.A. 26.6 N.A. N.A. 0
Percent
Protein Identity: 38.3 36.9 N.A. 37.8 N.A. N.A.
Protein Similarity: 55.2 55.5 N.A. 54.1 N.A. N.A.
P-Site Identity: 0 13.3 N.A. 26.6 N.A. N.A.
P-Site Similarity: 0 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 36 43 8 8 0 8 0 0 0 0 50 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 29 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % F
% Gly: 0 0 0 22 8 43 0 8 0 43 0 0 29 0 8 % G
% His: 0 0 0 0 0 0 0 8 8 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 15 8 8 8 8 8 36 0 0 8 8 0 0 0 0 % L
% Met: 0 0 0 0 15 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 0 8 0 8 8 36 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 8 0 8 8 0 8 0 8 0 0 8 0 22 0 15 % R
% Ser: 0 0 0 15 0 8 0 43 0 0 8 8 8 58 15 % S
% Thr: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % T
% Val: 36 15 0 0 15 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _