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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YRDC
All Species:
17.88
Human Site:
S218
Identified Species:
30.26
UniProt:
Q86U90
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U90
NP_078916.3
279
29328
S218
Q
D
L
W
P
Q
L
S
L
V
I
D
G
G
Q
Chimpanzee
Pan troglodytes
XP_513328
279
29381
S218
Q
D
L
W
P
Q
L
S
L
V
I
D
G
G
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539586
274
28633
S211
Q
D
L
W
P
Q
L
S
L
V
I
D
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U5F4
280
29435
S219
Q
D
L
W
P
H
L
S
L
V
I
D
G
G
P
Rat
Rattus norvegicus
Q499R4
280
29212
S219
Q
D
L
W
P
H
L
S
L
V
I
D
G
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511974
148
15850
I89
L
W
P
Q
L
S
L
I
V
D
G
G
P
I
G
Chicken
Gallus gallus
XP_417757
255
26969
L196
F
Q
D
L
W
P
Q
L
S
L
V
V
D
G
G
Frog
Xenopus laevis
NP_001082498
236
25547
P176
E
E
F
R
D
L
W
P
K
L
S
L
V
V
D
Zebra Danio
Brachydanio rerio
NP_001077336
235
25902
P176
N
E
F
E
D
L
W
P
R
L
A
V
V
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027444
248
27575
P189
S
E
F
R
S
L
W
P
Q
L
G
A
V
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793502
222
24027
S163
K
E
F
E
D
L
W
S
K
I
D
L
V
F
D
Poplar Tree
Populus trichocarpa
XP_002313460
232
24943
L173
C
I
K
D
F
E
N
L
W
N
R
C
A
Y
V
Maize
Zea mays
NP_001148954
275
29299
V211
L
S
G
Q
P
S
S
V
C
V
K
D
F
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974970
288
31285
A227
E
N
L
W
Q
H
C
A
Y
V
Y
D
G
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
84.2
N.A.
85.3
86
N.A.
39.4
61.6
53
50.1
N.A.
39.4
N.A.
N.A.
41.2
Protein Similarity:
100
99.6
N.A.
89.2
N.A.
89.2
90.3
N.A.
44.7
73.4
66.3
64.1
N.A.
58.4
N.A.
N.A.
55.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
6.6
6.6
0
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
13.3
20
20
13.3
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
38.3
36.9
N.A.
37.8
N.A.
N.A.
Protein Similarity:
55.2
55.5
N.A.
54.1
N.A.
N.A.
P-Site Identity:
0
20
N.A.
40
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% C
% Asp:
0
36
8
8
22
0
0
0
0
8
8
50
8
0
29
% D
% Glu:
15
29
0
15
0
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
0
29
0
8
0
0
0
0
0
0
0
8
15
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
15
8
43
50
22
% G
% His:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
8
36
0
0
8
0
% I
% Lys:
8
0
8
0
0
0
0
0
15
0
8
0
0
0
0
% K
% Leu:
15
0
43
8
8
29
43
15
36
29
0
15
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
43
8
0
22
0
0
0
0
8
0
22
% P
% Gln:
36
8
0
15
8
22
8
0
8
0
0
0
0
0
15
% Q
% Arg:
0
0
0
15
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
8
8
0
0
8
15
8
43
8
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
50
8
15
29
15
8
% V
% Trp:
0
8
0
43
8
0
29
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _