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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YRDC
All Species:
13.52
Human Site:
S274
Identified Species:
22.88
UniProt:
Q86U90
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U90
NP_078916.3
279
29328
S274
Q
K
Y
G
L
L
P
S
H
A
S
Y
L
_
_
Chimpanzee
Pan troglodytes
XP_513328
279
29381
S274
Q
K
Y
G
L
L
P
S
H
A
S
Y
L
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539586
274
28633
S267
Q
K
Y
G
L
L
P
S
H
G
S
G
S
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3U5F4
280
29435
S275
Q
K
Y
G
L
L
P
S
Q
G
S
C
S
_
_
Rat
Rattus norvegicus
Q499R4
280
29212
S275
G
K
Y
G
L
L
P
S
Q
G
S
C
S
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511974
148
15850
Chicken
Gallus gallus
XP_417757
255
26969
Frog
Xenopus laevis
NP_001082498
236
25547
Zebra Danio
Brachydanio rerio
NP_001077336
235
25902
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027444
248
27575
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793502
222
24027
Poplar Tree
Populus trichocarpa
XP_002313460
232
24943
Maize
Zea mays
NP_001148954
275
29299
G267
K
E
T
A
A
V
L
G
K
F
G
F
V
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974970
288
31285
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
84.2
N.A.
85.3
86
N.A.
39.4
61.6
53
50.1
N.A.
39.4
N.A.
N.A.
41.2
Protein Similarity:
100
99.6
N.A.
89.2
N.A.
89.2
90.3
N.A.
44.7
73.4
66.3
64.1
N.A.
58.4
N.A.
N.A.
55.2
P-Site Identity:
100
100
N.A.
66.6
N.A.
69.2
61.5
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
66.6
N.A.
69.2
61.5
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
38.3
36.9
N.A.
37.8
N.A.
N.A.
Protein Similarity:
55.2
55.5
N.A.
54.1
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
33.3
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
15
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
8
0
0
36
0
0
0
8
0
22
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
36
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
36
36
8
0
0
0
0
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% P
% Gln:
29
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
36
0
0
36
0
22
0
8
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
36
0
0
0
0
0
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
29
% _