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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YRDC All Species: 13.33
Human Site: S60 Identified Species: 22.56
UniProt: Q86U90 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U90 NP_078916.3 279 29328 S60 S G A V Q A A S P E R A G W T
Chimpanzee Pan troglodytes XP_513328 279 29381 S60 S G A V Q A A S P E R A G W T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539586 274 28633 W59 A S P E R A G W T E A L R A A
Cat Felis silvestris
Mouse Mus musculus Q3U5F4 280 29435 S61 S E P V E A A S P E R S G W T
Rat Rattus norvegicus Q499R4 280 29212 S61 S E A V E A A S P E R S G W T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511974 148 15850
Chicken Gallus gallus XP_417757 255 26969 G59 A V G A L Q E G G L V A V P T
Frog Xenopus laevis NP_001082498 236 25547 Q40 T S L G I L Q Q G G V I G V P
Zebra Danio Brachydanio rerio NP_001077336 235 25902 A40 C T V N A L K A G Q V V A V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027444 248 27575 V53 Q C L L G G Q V I A L P T D T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793502 222 24027 S27 L A A N S L M S G N V I S V P
Poplar Tree Populus trichocarpa XP_002313460 232 24943 G37 A I E A L K A G K V I A V P T
Maize Zea mays NP_001148954 275 29299 A60 N T A H R I D A T A E N I F P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974970 288 31285 P70 S K S C L V H P A T E A Y A Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 84.2 N.A. 85.3 86 N.A. 39.4 61.6 53 50.1 N.A. 39.4 N.A. N.A. 41.2
Protein Similarity: 100 99.6 N.A. 89.2 N.A. 89.2 90.3 N.A. 44.7 73.4 66.3 64.1 N.A. 58.4 N.A. N.A. 55.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 73.3 80 N.A. 0 13.3 6.6 0 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 26.6 N.A. 86.6 93.3 N.A. 0 20 13.3 13.3 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: 38.3 36.9 N.A. 37.8 N.A. N.A.
Protein Similarity: 55.2 55.5 N.A. 54.1 N.A. N.A.
P-Site Identity: 20 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 36 15 8 36 36 15 8 15 8 36 8 15 8 % A
% Cys: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % D
% Glu: 0 15 8 8 15 0 8 0 0 36 15 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 15 8 8 8 8 8 15 29 8 0 0 36 0 0 % G
% His: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 8 0 0 8 0 8 15 8 0 0 % I
% Lys: 0 8 0 0 0 8 8 0 8 0 0 0 0 0 0 % K
% Leu: 8 0 15 8 22 22 0 0 0 8 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 15 0 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 15 0 0 0 0 8 29 0 0 8 0 15 29 % P
% Gln: 8 0 0 0 15 8 15 8 0 8 0 0 0 0 8 % Q
% Arg: 0 0 0 0 15 0 0 0 0 0 29 0 8 0 0 % R
% Ser: 36 15 8 0 8 0 0 36 0 0 0 15 8 0 0 % S
% Thr: 8 15 0 0 0 0 0 0 15 8 0 0 8 0 50 % T
% Val: 0 8 8 29 0 8 0 8 0 8 29 8 15 22 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 29 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _