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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YRDC All Species: 17.58
Human Site: T167 Identified Species: 29.74
UniProt: Q86U90 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U90 NP_078916.3 279 29328 T167 N K D L N P F T P L V G I R I
Chimpanzee Pan troglodytes XP_513328 279 29381 T167 N K D L N P F T P L V G I R I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539586 274 28633 T160 N R D L N P C T P L V G V R I
Cat Felis silvestris
Mouse Mus musculus Q3U5F4 280 29435 T168 N K D L N P F T R L V G I R I
Rat Rattus norvegicus Q499R4 280 29212 T168 N K D L N P F T P L V G I R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511974 148 15850 R50 I P R H A F M R Q L V Q K F S
Chicken Gallus gallus XP_417757 255 26969 P157 G V R I P N H P F I R E L A R
Frog Xenopus laevis NP_001082498 236 25547 D137 L V G V R I P D H A F I R Q L
Zebra Danio Brachydanio rerio NP_001077336 235 25902 D137 L I G V R I P D H P F M R R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027444 248 27575 F150 I G I R I P D F N F M R D L C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793502 222 24027 E124 L I G L R I P E Y P F I Q Q L
Poplar Tree Populus trichocarpa XP_002313460 232 24943 V134 L D S V G V R V P D C N F I R
Maize Zea mays NP_001148954 275 29299 P171 I L E R S L N P G L D S I G V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974970 288 31285 P174 I L E K S L N P G I G T I G V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 84.2 N.A. 85.3 86 N.A. 39.4 61.6 53 50.1 N.A. 39.4 N.A. N.A. 41.2
Protein Similarity: 100 99.6 N.A. 89.2 N.A. 89.2 90.3 N.A. 44.7 73.4 66.3 64.1 N.A. 58.4 N.A. N.A. 55.2
P-Site Identity: 100 100 N.A. 80 N.A. 93.3 100 N.A. 13.3 0 0 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 100 N.A. 13.3 20 20 20 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: 38.3 36.9 N.A. 37.8 N.A. N.A.
Protein Similarity: 55.2 55.5 N.A. 54.1 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 8 % C
% Asp: 0 8 36 0 0 0 8 15 0 8 8 0 8 0 0 % D
% Glu: 0 0 15 0 0 0 0 8 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 29 8 8 8 22 0 8 8 0 % F
% Gly: 8 8 22 0 8 0 0 0 15 0 8 36 0 15 0 % G
% His: 0 0 0 8 0 0 8 0 15 0 0 0 0 0 0 % H
% Ile: 29 15 8 8 8 22 0 0 0 15 0 15 43 8 36 % I
% Lys: 0 29 0 8 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 29 15 0 43 0 15 0 0 0 50 0 0 8 8 22 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 0 % M
% Asn: 36 0 0 0 36 8 15 0 8 0 0 8 0 0 0 % N
% Pro: 0 8 0 0 8 43 22 22 36 15 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 8 8 15 0 % Q
% Arg: 0 8 15 15 22 0 8 8 8 0 8 8 15 43 15 % R
% Ser: 0 0 8 0 15 0 0 0 0 0 0 8 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 36 0 0 0 8 0 0 0 % T
% Val: 0 15 0 22 0 8 0 8 0 0 43 0 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _