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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YRDC All Species: 17.88
Human Site: Y107 Identified Species: 30.26
UniProt: Q86U90 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U90 NP_078916.3 279 29328 Y107 S A A L R A V Y R L K G R S E
Chimpanzee Pan troglodytes XP_513328 279 29381 Y107 S A A L R A V Y R L K G R S E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539586 274 28633 R101 A A L D A V Y R L K G R S H A
Cat Felis silvestris
Mouse Mus musculus Q3U5F4 280 29435 Y108 S A A L S C V Y R L K G R S E
Rat Rattus norvegicus Q499R4 280 29212 Y108 S A A L S C V Y R L K G R S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511974 148 15850
Chicken Gallus gallus XP_417757 255 26969 G102 K P L A I C L G D V E H I Y R
Frog Xenopus laevis NP_001082498 236 25547 C82 G T K P L A I C V G N V E D I
Zebra Danio Brachydanio rerio NP_001077336 235 25902 C82 G D K P L A I C V G E I H D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027444 248 27575 N95 P V A I C V H N I D A L R R F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793502 222 24027 C69 G N K P I A I C I N C I E D I
Poplar Tree Populus trichocarpa XP_002313460 232 24943 V79 T S P L A I C V G D V S Q I Q
Maize Zea mays NP_001148954 275 29299 Y110 A G A V N R I Y E I K G R I Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974970 288 31285 Y113 L E A V S R I Y E I K G R K L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 84.2 N.A. 85.3 86 N.A. 39.4 61.6 53 50.1 N.A. 39.4 N.A. N.A. 41.2
Protein Similarity: 100 99.6 N.A. 89.2 N.A. 89.2 90.3 N.A. 44.7 73.4 66.3 64.1 N.A. 58.4 N.A. N.A. 55.2
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 86.6 N.A. 0 0 6.6 6.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 86.6 N.A. 0 20 13.3 20 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: 38.3 36.9 N.A. 37.8 N.A. N.A.
Protein Similarity: 55.2 55.5 N.A. 54.1 N.A. N.A.
P-Site Identity: 6.6 33.3 N.A. 33.3 N.A. N.A.
P-Site Similarity: 33.3 66.6 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 36 50 8 15 36 0 0 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 8 22 8 22 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 8 15 0 0 0 22 0 % D
% Glu: 0 8 0 0 0 0 0 0 15 0 15 0 15 0 29 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 22 8 0 0 0 0 0 8 8 15 8 43 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 8 8 8 0 % H
% Ile: 0 0 0 8 15 8 36 0 15 15 0 15 8 15 22 % I
% Lys: 8 0 22 0 0 0 0 0 0 8 43 0 0 8 0 % K
% Leu: 8 0 15 36 15 0 8 0 8 29 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 8 0 8 8 0 0 0 0 % N
% Pro: 8 8 8 22 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 15 % Q
% Arg: 0 0 0 0 15 15 0 8 29 0 0 8 50 8 8 % R
% Ser: 29 8 0 0 22 0 0 0 0 0 0 8 8 29 0 % S
% Thr: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 15 0 15 29 8 15 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 43 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _