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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YRDC All Species: 20.61
Human Site: Y129 Identified Species: 34.87
UniProt: Q86U90 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U90 NP_078916.3 279 29328 Y129 L G R V A D V Y R Y C R V R V
Chimpanzee Pan troglodytes XP_513328 279 29381 Y129 L G R V A D V Y R Y C R V R V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539586 274 28633 Y122 L G R V A D V Y R Y C R V S V
Cat Felis silvestris
Mouse Mus musculus Q3U5F4 280 29435 Y130 L G R V A D V Y R Y C Q V R V
Rat Rattus norvegicus Q499R4 280 29212 Y130 L G R V A D V Y R Y C Q V R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511974 148 15850 G16 A R G A A P D G G R R R V D F
Chicken Gallus gallus XP_417757 255 26969 L123 P D E L L Q D L L P G P V T L
Frog Xenopus laevis NP_001082498 236 25547 R103 N V P D Q L L R D L L P G P V
Zebra Danio Brachydanio rerio NP_001077336 235 25902 R103 S V K D R L L R D L L P G P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027444 248 27575 L116 S D E L L T R L L P G P L T I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793502 222 24027 R90 T V S D D I L R D L L P G P V
Poplar Tree Populus trichocarpa XP_002313460 232 24943 D100 Y L P H G L L D S L L P G P V
Maize Zea mays NP_001148954 275 29299 S132 V G D V S D I S R F A L V D H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974970 288 31285 K135 V G D V L D I K R V A T T S H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 84.2 N.A. 85.3 86 N.A. 39.4 61.6 53 50.1 N.A. 39.4 N.A. N.A. 41.2
Protein Similarity: 100 99.6 N.A. 89.2 N.A. 89.2 90.3 N.A. 44.7 73.4 66.3 64.1 N.A. 58.4 N.A. N.A. 55.2
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 20 6.6 6.6 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 20 20 13.3 20 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: 38.3 36.9 N.A. 37.8 N.A. N.A.
Protein Similarity: 55.2 55.5 N.A. 54.1 N.A. N.A.
P-Site Identity: 6.6 33.3 N.A. 26.6 N.A. N.A.
P-Site Similarity: 13.3 60 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 43 0 0 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 % C
% Asp: 0 15 15 22 8 50 15 8 22 0 0 0 0 15 0 % D
% Glu: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % F
% Gly: 0 50 8 0 8 0 0 8 8 0 15 0 29 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 15 % H
% Ile: 0 0 0 0 0 8 15 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 36 8 0 15 22 22 29 15 15 29 29 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 15 0 0 8 0 0 0 15 0 43 0 29 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 15 0 0 0 % Q
% Arg: 0 8 36 0 8 0 8 22 50 8 8 29 0 29 0 % R
% Ser: 15 0 8 0 8 0 0 8 8 0 0 0 0 15 0 % S
% Thr: 8 0 0 0 0 8 0 0 0 0 0 8 8 15 0 % T
% Val: 15 22 0 50 0 0 36 0 0 8 0 0 58 0 65 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 36 0 36 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _