KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YRDC
All Species:
17.27
Human Site:
Y131
Identified Species:
29.23
UniProt:
Q86U90
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U90
NP_078916.3
279
29328
Y131
R
V
A
D
V
Y
R
Y
C
R
V
R
V
P
E
Chimpanzee
Pan troglodytes
XP_513328
279
29381
Y131
R
V
A
D
V
Y
R
Y
C
R
V
R
V
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539586
274
28633
Y124
R
V
A
D
V
Y
R
Y
C
R
V
S
V
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3U5F4
280
29435
Y132
R
V
A
D
V
Y
R
Y
C
Q
V
R
V
P
R
Rat
Rattus norvegicus
Q499R4
280
29212
Y132
R
V
A
D
V
Y
R
Y
C
Q
V
R
V
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511974
148
15850
R18
G
A
A
P
D
G
G
R
R
R
V
D
F
R
P
Chicken
Gallus gallus
XP_417757
255
26969
P125
E
L
L
Q
D
L
L
P
G
P
V
T
L
V
L
Frog
Xenopus laevis
NP_001082498
236
25547
L105
P
D
Q
L
L
R
D
L
L
P
G
P
V
T
L
Zebra Danio
Brachydanio rerio
NP_001077336
235
25902
L105
K
D
R
L
L
R
D
L
L
P
G
P
V
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027444
248
27575
P118
E
L
L
T
R
L
L
P
G
P
L
T
I
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793502
222
24027
L92
S
D
D
I
L
R
D
L
L
P
G
P
V
T
V
Poplar Tree
Populus trichocarpa
XP_002313460
232
24943
L102
P
H
G
L
L
D
S
L
L
P
G
P
V
T
V
Maize
Zea mays
NP_001148954
275
29299
F134
D
V
S
D
I
S
R
F
A
L
V
D
H
L
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974970
288
31285
V137
D
V
L
D
I
K
R
V
A
T
T
S
H
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
84.2
N.A.
85.3
86
N.A.
39.4
61.6
53
50.1
N.A.
39.4
N.A.
N.A.
41.2
Protein Similarity:
100
99.6
N.A.
89.2
N.A.
89.2
90.3
N.A.
44.7
73.4
66.3
64.1
N.A.
58.4
N.A.
N.A.
55.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
20
6.6
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
20
20
13.3
20
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
38.3
36.9
N.A.
37.8
N.A.
N.A.
Protein Similarity:
55.2
55.5
N.A.
54.1
N.A.
N.A.
P-Site Identity:
6.6
26.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
13.3
46.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
43
0
0
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
36
0
0
0
0
0
0
% C
% Asp:
15
22
8
50
15
8
22
0
0
0
0
15
0
0
0
% D
% Glu:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
0
8
8
0
15
0
29
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
8
15
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
22
22
29
15
15
29
29
8
8
0
8
15
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
8
0
0
0
15
0
43
0
29
0
36
22
% P
% Gln:
0
0
8
8
0
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
36
0
8
0
8
22
50
8
8
29
0
29
0
8
15
% R
% Ser:
8
0
8
0
0
8
8
0
0
0
0
15
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
8
15
0
29
0
% T
% Val:
0
50
0
0
36
0
0
8
0
0
58
0
65
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
36
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _