KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF39
All Species:
19.7
Human Site:
S401
Identified Species:
43.33
UniProt:
Q86UA1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UA1
NP_060392.3
669
78430
S401
A
K
Y
M
E
N
H
S
I
E
G
V
R
H
V
Chimpanzee
Pan troglodytes
XP_001151081
664
77842
S396
A
K
Y
M
E
N
H
S
I
E
G
V
R
H
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851059
548
64272
E318
E
Q
Q
G
N
I
N
E
A
R
N
I
L
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z2
665
77903
S399
A
K
Y
M
E
N
H
S
I
E
G
V
R
H
V
Rat
Rattus norvegicus
NP_001101496
299
34936
G69
E
T
N
S
T
I
R
G
T
F
E
H
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514648
669
78057
S401
A
K
Y
M
E
N
H
S
T
E
G
V
R
H
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLU2
641
74544
A389
R
A
C
H
V
H
L
A
K
K
P
M
V
H
L
Zebra Danio
Brachydanio rerio
Q1JPZ7
752
85928
S476
A
K
Y
L
E
S
Y
S
T
E
A
V
R
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW8
1066
120527
E753
L
R
Y
L
E
S
L
E
D
Q
S
G
V
V
D
Honey Bee
Apis mellifera
XP_392380
946
108879
K632
V
R
Y
L
E
S
L
K
G
D
N
V
E
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793456
813
92707
S505
A
R
F
M
E
K
T
S
Q
E
A
A
S
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
78.7
N.A.
93.4
41.1
N.A.
87.8
N.A.
65.4
58.7
N.A.
28.6
33
N.A.
37.1
Protein Similarity:
100
99.2
N.A.
80.8
N.A.
96.5
43.6
N.A.
93.7
N.A.
79.2
73.2
N.A.
41.5
46.8
N.A.
50.6
P-Site Identity:
100
100
N.A.
0
N.A.
100
0
N.A.
93.3
N.A.
6.6
60
N.A.
13.3
20
N.A.
40
P-Site Similarity:
100
100
N.A.
20
N.A.
100
6.6
N.A.
93.3
N.A.
40
86.6
N.A.
40
53.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
10
0
0
0
0
0
10
10
0
19
10
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% D
% Glu:
19
0
0
0
73
0
0
19
0
55
10
0
10
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
10
0
37
10
0
0
0
% G
% His:
0
0
0
10
0
10
37
0
0
0
0
10
0
55
0
% H
% Ile:
0
0
0
0
0
19
0
0
28
0
0
10
0
0
19
% I
% Lys:
0
46
0
0
0
10
0
10
10
10
0
0
0
10
0
% K
% Leu:
10
0
0
28
0
0
28
0
0
0
0
0
10
0
19
% L
% Met:
0
0
0
46
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
10
37
10
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
10
28
0
0
0
0
10
0
0
10
0
0
46
10
0
% R
% Ser:
0
0
0
10
0
28
0
55
0
0
10
0
10
0
0
% S
% Thr:
0
10
0
0
10
0
10
0
28
0
0
0
0
0
10
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
55
19
19
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
64
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _