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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF39
All Species:
21.82
Human Site:
S491
Identified Species:
48
UniProt:
Q86UA1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UA1
NP_060392.3
669
78430
S491
N
A
K
S
N
N
E
S
S
F
Y
A
V
K
L
Chimpanzee
Pan troglodytes
XP_001151081
664
77842
S486
N
A
K
S
N
N
E
S
S
F
Y
A
V
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851059
548
64272
H380
Y
A
I
K
L
A
R
H
L
F
K
I
Q
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z2
665
77903
S489
N
A
K
S
N
N
E
S
S
F
Y
A
I
K
L
Rat
Rattus norvegicus
NP_001101496
299
34936
Q131
Q
R
F
K
E
H
V
Q
N
N
L
P
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514648
669
78057
S491
N
A
K
S
S
N
E
S
S
F
Y
A
I
K
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLU2
641
74544
S462
K
T
K
T
S
S
E
S
S
F
Y
A
I
K
L
Zebra Danio
Brachydanio rerio
Q1JPZ7
752
85928
S566
N
G
R
N
S
S
E
S
S
F
Y
S
V
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW8
1066
120527
A848
S
T
K
N
K
G
I
A
G
S
L
A
I
K
Y
Honey Bee
Apis mellifera
XP_392380
946
108879
A725
N
S
K
N
R
T
I
A
N
N
I
V
V
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793456
813
92707
Q595
D
A
K
T
A
T
G
Q
S
F
F
A
G
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
78.7
N.A.
93.4
41.1
N.A.
87.8
N.A.
65.4
58.7
N.A.
28.6
33
N.A.
37.1
Protein Similarity:
100
99.2
N.A.
80.8
N.A.
96.5
43.6
N.A.
93.7
N.A.
79.2
73.2
N.A.
41.5
46.8
N.A.
50.6
P-Site Identity:
100
100
N.A.
20
N.A.
93.3
6.6
N.A.
86.6
N.A.
60
60
N.A.
20
26.6
N.A.
46.6
P-Site Similarity:
100
100
N.A.
20
N.A.
100
20
N.A.
100
N.A.
86.6
93.3
N.A.
46.6
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
10
10
0
19
0
0
0
64
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
10
0
55
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
73
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
10
0
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
19
0
0
0
10
10
37
0
0
% I
% Lys:
10
0
73
19
10
0
0
0
0
0
10
0
0
91
0
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
19
0
0
0
73
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
55
0
0
28
28
37
0
0
19
19
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
19
0
0
0
0
10
0
0
% Q
% Arg:
0
10
10
0
10
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
10
10
0
37
28
19
0
55
64
10
0
10
0
0
0
% S
% Thr:
0
19
0
19
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
37
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
55
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _