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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF39
All Species:
15.15
Human Site:
S603
Identified Species:
33.33
UniProt:
Q86UA1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UA1
NP_060392.3
669
78430
S603
T
L
L
K
E
Q
D
S
L
K
R
K
A
E
N
Chimpanzee
Pan troglodytes
XP_001151081
664
77842
S598
T
L
L
K
E
Q
D
S
L
K
R
K
A
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851059
548
64272
L483
L
L
K
E
Q
D
S
L
K
R
K
A
E
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z2
665
77903
Q599
H
Q
T
L
L
K
E
Q
D
T
L
K
R
K
A
Rat
Rattus norvegicus
NP_001101496
299
34936
N234
L
E
K
A
Q
L
K
N
W
K
E
Y
L
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514648
669
78057
S603
A
L
L
K
E
Q
D
S
L
K
R
K
A
E
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLU2
641
74544
I574
K
L
L
K
H
Q
D
I
V
K
R
K
A
E
N
Zebra Danio
Brachydanio rerio
Q1JPZ7
752
85928
S678
R
L
L
A
E
Q
E
S
F
K
R
K
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW8
1066
120527
E960
Q
A
L
T
K
A
K
E
A
Q
K
K
S
D
G
Honey Bee
Apis mellifera
XP_392380
946
108879
E837
K
C
I
K
Q
A
K
E
R
K
K
T
K
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793456
813
92707
S710
K
L
V
K
N
I
S
S
S
K
K
R
S
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
78.7
N.A.
93.4
41.1
N.A.
87.8
N.A.
65.4
58.7
N.A.
28.6
33
N.A.
37.1
Protein Similarity:
100
99.2
N.A.
80.8
N.A.
96.5
43.6
N.A.
93.7
N.A.
79.2
73.2
N.A.
41.5
46.8
N.A.
50.6
P-Site Identity:
100
100
N.A.
6.6
N.A.
6.6
13.3
N.A.
93.3
N.A.
73.3
73.3
N.A.
13.3
13.3
N.A.
26.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
26.6
26.6
N.A.
93.3
N.A.
80
80
N.A.
46.6
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
19
0
19
0
0
10
0
0
10
46
10
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
37
0
10
0
0
0
0
10
19
% D
% Glu:
0
10
0
10
37
0
19
19
0
0
10
0
10
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% G
% His:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
28
0
19
55
10
10
28
0
10
73
37
64
10
10
0
% K
% Leu:
19
64
55
10
10
10
0
10
28
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
0
19
46
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
28
46
0
10
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
10
10
46
10
10
0
0
% R
% Ser:
0
0
0
0
0
0
19
46
10
0
0
0
19
0
0
% S
% Thr:
19
0
10
10
0
0
0
0
0
10
0
10
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _